SCOPe 2.08: Domain d5in3a1: 5in3 A:28-197

Lineage for d5in3a1 (5in3 A:28-197)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.13: HIT-like [54196] (2 superfamilies)
   alpha-beta(3)-alpha-beta(2); 3 layers: alpha/beta/alpha

4. Superfamily d.13.1: HIT-like [54197] (6 families)

5. Family d.13.1.2: Hexose-1-phosphate uridylyltransferase [54207] (1 protein)
   duplication: consists of 2 HIT-like motifs
   binds zinc and iron ions

6. Protein Galactose-1-phosphate uridylyltransferase [54208] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [315092] (2 PDB entries)

8. Domain d5in3a1: 5in3 A:28-197 [315093]
   automated match to d1guqa1
   complexed with edo, g1p, h2u, zn

Details for d5in3a1

PDB Entry: 5in3, 1.73 Å

PDB Description: crystal structure of glucose-1-phosphate bound nucleotidylated human galactose-1-phosphate uridylyltransferase

PDB Compounds: (A:) galactose-1-phosphate uridylyltransferase

SCOPe Domain Sequences for d5in3a1:

Sequence, based on SEQRES records:

>d5in3a1 d.13.1.2 (A:28-197) Galactose-1-phosphate uridylyltransferase {Human (Homo sapiens) [TaxId: 9606]}
dhqhirynplqdewvlvsahrmkrpwqgqvepqllktvprhdplnplcpgairangevnp
qydstflfdndfpalqpdapspgpsdhplfqaksargvckvmcfhpwsdvtlplmsvpei
ravvdawasvteelgaqypwvqifenkgammgcsnphphcqvwassflpd

Sequence, based on observed residues (ATOM records):

>d5in3a1 d.13.1.2 (A:28-197) Galactose-1-phosphate uridylyltransferase {Human (Homo sapiens) [TaxId: 9606]}
dhqhirynplqdewvlvsahrtvprhdplnplcpgairangevnpqydstflfdndfpal
qpdapspgpsdhplfqaksargvckvmcfhpwsdvtlplmsvpeiravvdawasvteelg
aqypwvqifenkgammgcsnphphcqvwassflpd

Timeline for d5in3a1:

• d5in3a1 first appeared in SCOPe 2.06
  
• d5in3a1 appears in SCOPe 2.07