Lineage for d5i2rd1 (5i2r D:457-768)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2342123Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 2342124Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families) (S)
  5. 2342564Family a.211.1.0: automated matches [191566] (1 protein)
    not a true family
  6. 2342565Protein automated matches [190983] (9 species)
    not a true protein
  7. 2342579Species Human (Homo sapiens) [TaxId:9606] [188676] (127 PDB entries)
  8. 2342827Domain d5i2rd1: 5i2r D:457-768 [315034]
    Other proteins in same PDB: d5i2rd2
    automated match to d5axqb_
    complexed with 67a, mg, zn

Details for d5i2rd1

PDB Entry: 5i2r (more details), 2.5 Å

PDB Description: human pde10a in complex with 3-(2-phenylpyrazol-3-yl)-1-[3- (trifluoromethoxy)phenyl]pyridazin-4-one
PDB Compounds: (D:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d5i2rd1:

Sequence; same for both SEQRES and ATOM records: (download)

>d5i2rd1 a.211.1.0 (D:457-768) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfeleklcrfimsvk
knyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhrgfsnsylq
kfdhplaalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdla
lyfgnrkqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvtkltandiyaef
waegdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilpptepllkacr
dnlsqwekvirg

SCOPe Domain Coordinates for d5i2rd1:

Click to download the PDB-style file with coordinates for d5i2rd1.
(The format of our PDB-style files is described here.)

Timeline for d5i2rd1: