Lineage for d5hnra_ (5hnr A:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2413227Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2420459Superfamily c.1.10: Aldolase [51569] (9 families) (S)
    Common fold covers whole protein structure
  5. 2421381Family c.1.10.3: 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51594] (2 protein domains)
    hybrid of classes I and II aldolase
    automatically mapped to Pfam PF00490
  6. 2421382Protein 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) [51595] (5 species)
  7. 2421404Species Human (Homo sapiens) [TaxId:9606] [63921] (4 PDB entries)
  8. 2421411Domain d5hnra_: 5hnr A: [314831]
    automated match to d1e51a_
    complexed with dav, so4, zn

Details for d5hnra_

PDB Entry: 5hnr (more details), 2.83 Å

PDB Description: the x-ray structure of octameric human native 5-aminolaevulinic acid dehydratase.
PDB Compounds: (A:) delta-aminolevulinic acid dehydratase

SCOPe Domain Sequences for d5hnra_:

Sequence, based on SEQRES records: (download)

>d5hnra_ c.1.10.3 (A:) 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) {Human (Homo sapiens) [TaxId: 9606]}
mqpqsvlhsgyfhpllrawqtatttlnasnliypifvtdvpddiqpitslpgvarygvkr
leemlrplveeglrcvlifgvpsrvpkdergsaadseespaieaihllrktfpnllvacd
vclcpytshghcgllsengafraeesrqrlaevalayakagcqvvapsdmmdgrveaike
almahglgnrvsvmsysakfascfygpfrdaaksspafgdrrcyqlppgarglalravdr
dvregadmlmvkpgmpyldivrevkdkhpdlplavyhvsgefamlwhgaqagafdlkaav
leamtafrragadiiityytpqllqwlk

Sequence, based on observed residues (ATOM records): (download)

>d5hnra_ c.1.10.3 (A:) 5-aminolaevulinate dehydratase, ALAD (porphobilinogen synthase) {Human (Homo sapiens) [TaxId: 9606]}
mqpqsvlhsgyfhpllrawqtatttlnasnliypifvtdvpddiqpitslpgvarygvkr
leemlrplveeglrcvlifgvpsrvpkdergsaadseespaieaihllrktfpnllvacd
vclcpytshghcgllsgafraeesrqrlaevalayakagcqvvapsdmmdgrveaikeal
mahglgnrvsvmsysakfascfygpfrdaaksspafgdrrcyqlppgarglalravdrdv
regadmlmvkpgmpyldivrevkdkhpdlplavyhvsgefamlwhgaqagafdlkaavle
amtafrragadiiityytpqllqwlk

SCOPe Domain Coordinates for d5hnra_:

Click to download the PDB-style file with coordinates for d5hnra_.
(The format of our PDB-style files is described here.)

Timeline for d5hnra_: