Lineage for d5hmia_ (5hmi A:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2325522Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  4. 2325523Superfamily a.42.1: SWIB/MDM2 domain [47592] (2 families) (S)
    binds to the transactivation domain of human p53
  5. 2325524Family a.42.1.1: SWIB/MDM2 domain [47593] (5 proteins)
    Pfam PF02201
  6. 2325531Protein MDM2 [47594] (2 species)
  7. 2325549Species Human (Homo sapiens) [TaxId:9606] [47596] (76 PDB entries)
  8. 2325615Domain d5hmia_: 5hmi A: [314804]
    Other proteins in same PDB: d5hmib2
    automated match to d1ttva_
    complexed with 62t, so4

Details for d5hmia_

PDB Entry: 5hmi (more details), 1.74 Å

PDB Description: hdm2 in complex with a 3,3-disubstituted piperidine
PDB Compounds: (A:) E3 ubiquitin-protein ligase Mdm2

SCOPe Domain Sequences for d5hmia_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5hmia_ a.42.1.1 (A:) MDM2 {Human (Homo sapiens) [TaxId: 9606]}
qipaseqetlvrpkplllkllksvgaqkdtytmkevlyylgqyimtkrlydekqqhivhc
sndllgdlfgvpsfsvkehrkiytmiyrnlvvvnqq

SCOPe Domain Coordinates for d5hmia_:

Click to download the PDB-style file with coordinates for d5hmia_.
(The format of our PDB-style files is described here.)

Timeline for d5hmia_: