SCOPe 2.08: Domain d5fqva_: 5fqv A:

Lineage for d5fqva_ (5fqv A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (171 PDB entries)

8. Domain d5fqva_: 5fqv A: [314485]
   automated match to d3uucd_
   complexed with vqi

Details for d5fqva_

PDB Entry: 5fqv, 1.74 Å

PDB Description: selective estrogen receptor downregulator antagonists: tetrahydroisoquinoline phenols 5.

PDB Compounds: (A:) Estrogen receptor alpha

SCOPe Domain Sequences for d5fqva_:

Sequence, based on SEQRES records:

>d5fqva_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvpg
fvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifd
mllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtl
ihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvpsydlllemld

Sequence, based on observed residues (ATOM records):

>d5fqva_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpfsmmglltnladrelvhminwakrvpgfvd
ltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifdmll
atssrfrmmnlqgeefvclksiillnsgvytftlksleekdhihrvldkitdtlihlmak
agltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvpsydlllemld

Timeline for d5fqva_:

• d5fqva_ first appeared in SCOPe 2.06
  
• d5fqva_ appears in SCOPe 2.07