Lineage for d5flfa_ (5flf A:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2979693Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2981340Protein Fibroblast growth factor receptor 1 [56158] (1 species)
    PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase
  7. 2981341Species Human (Homo sapiens) [TaxId:9606] [56159] (47 PDB entries)
  8. 2981426Domain d5flfa_: 5flf A: [314467]
    automated match to d4v04b_
    complexed with act, cl, pge, so4; mutant

Details for d5flfa_

PDB Entry: 5flf (more details), 2.58 Å

PDB Description: disease linked mutation in fgfr
PDB Compounds: (A:) fibroblast growth factor receptor 1

SCOPe Domain Sequences for d5flfa_:

Sequence, based on SEQRES records: (download)

>d5flfa_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
vseyelpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksd
atekdlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrpp
gleysynpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmki
adfglardihhidyykkttngrlpvkwmapealfdgiythqsdvwsfgvllweiftlggs
pypgvpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldriva
lts

Sequence, based on observed residues (ATOM records): (download)

>d5flfa_ d.144.1.7 (A:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
vseyelpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksd
atekdlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrpp
gleyseeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfglar
dihhidyykkttngrlpvkwmapealfdgiythqsdvwsfgvllweiftlggspypgvpv
eelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivalts

SCOPe Domain Coordinates for d5flfa_:

Click to download the PDB-style file with coordinates for d5flfa_.
(The format of our PDB-style files is described here.)

Timeline for d5flfa_: