Lineage for d5ew9a_ (5ew9 A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2542390Protein Aurora-related kinase 1 (aurora-2) [90038] (1 species)
    OPK group; AIRK subfamily; serine/threonine kinase
  7. 2542391Species Human (Homo sapiens) [TaxId:9606] [90039] (72 PDB entries)
  8. 2542425Domain d5ew9a_: 5ew9 A: [314338]
    automated match to d4deea_
    complexed with 5vc

Details for d5ew9a_

PDB Entry: 5ew9 (more details), 2.18 Å

PDB Description: crystal structure of aurora a kinase domain bound to mk-5108
PDB Compounds: (A:) Aurora kinase A

SCOPe Domain Sequences for d5ew9a_:

Sequence, based on SEQRES records: (download)

>d5ew9a_ d.144.1.7 (A:) Aurora-related kinase 1 (aurora-2) {Human (Homo sapiens) [TaxId: 9606]}
qwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqs
hlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsy
chskrvihrdikpenlllgsagelkiadfgwsvhapssrrttlcgtldylppemiegrmh
dekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkh
npsqrpmlrevlehpwitansskp

Sequence, based on observed residues (ATOM records): (download)

>d5ew9a_ d.144.1.7 (A:) Aurora-related kinase 1 (aurora-2) {Human (Homo sapiens) [TaxId: 9606]}
qwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqs
hlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsy
chskrvihrdikpenlllgsagelkiadfgwsvhrttlcgtldylppemiegrmhdekvd
lwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqr
pmlrevlehpwitansskp

SCOPe Domain Coordinates for d5ew9a_:

Click to download the PDB-style file with coordinates for d5ew9a_.
(The format of our PDB-style files is described here.)

Timeline for d5ew9a_: