SCOPe 2.06: Domain d5ei4a1: 5ei4 A:44-168

Lineage for d5ei4a1 (5ei4 A:44-168)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (647 PDB entries)

8. Domain d5ei4a1: 5ei4 A:44-168 [313798]
   Other proteins in same PDB: d5ei4a2
   automated match to d4hbwa_
   complexed with 5nv, edo

Details for d5ei4a1

PDB Entry: 5ei4, 1.05 Å

PDB Description: first domain of human bromodomain brd4 in complex with inhibitor 8-(5- amino-1h-[1,2,4]triazol-3-ylsulfanylmethyl)-3-(4-chlorobenzyl)-7- ethyl-3,7-dihydropurine-2,6-dione

PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d5ei4a1:

Sequence; same for both SEQRES and ATOM records:

>d5ei4a1 a.29.2.0 (A:44-168) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiikt
pmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkine
lptee

Timeline for d5ei4a1:

• d5ei4a1 is new in SCOPe 2.06-stable
  
• d5ei4a1 appears in SCOPe 2.07
  
• d5ei4a1 appears in the current release, SCOPe 2.08