Lineage for d5edgb1 (5edg B:457-770)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2342123Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 2342124Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families) (S)
  5. 2342564Family a.211.1.0: automated matches [191566] (1 protein)
    not a true family
  6. 2342565Protein automated matches [190983] (9 species)
    not a true protein
  7. 2342579Species Human (Homo sapiens) [TaxId:9606] [188676] (122 PDB entries)
  8. 2342796Domain d5edgb1: 5edg B:457-770 [313692]
    Other proteins in same PDB: d5edgb2, d5edgd2
    automated match to d5axqb_
    complexed with 5mg, mg, zn

Details for d5edgb1

PDB Entry: 5edg (more details), 2.3 Å

PDB Description: human pde10a in complex with 3-(2-chloro-5-phenyl-3h-imidazol-4-yl)-1- (3-trifluoromethoxy-phenyl)-1h-pyridazin-4-one at 2.30a
PDB Compounds: (B:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d5edgb1:

Sequence; same for both SEQRES and ATOM records: (download)

>d5edgb1 a.211.1.0 (B:457-770) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qglmqftlpvrlcreielfhfdigpfenmwpgifvymvhrscgtscfeleklcrfimsvk
knyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhrgfsnsylq
kfdhplaalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdla
lyfgnrkqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvtkltandiyaef
waegdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilpptepllkacr
dnlsqwekvirgee

SCOPe Domain Coordinates for d5edgb1:

Click to download the PDB-style file with coordinates for d5edgb1.
(The format of our PDB-style files is described here.)

Timeline for d5edgb1: