SCOPe 2.08: Domain d5eg3a_: 5eg3 A:

Lineage for d5eg3a_ (5eg3 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d5eg3a_: 5eg3 A: [313676]
   Other proteins in same PDB: d5eg3b_
   automated match to d3gqla_
   complexed with acp, mg

Details for d5eg3a_

PDB Entry: 5eg3, 2.61 Å

PDB Description: crystal structure of the activated fgf receptor 2 (fgfr2) kinase domain in complex with the csh2 domain of phospholipase c gamma (plcgamma)

PDB Compounds: (A:) Fibroblast growth factor receptor 2

SCOPe Domain Sequences for d5eg3a_:

Sequence, based on SEQRES records:

>d5eg3a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
felpedpkwefprdkltlgkplgegafgqvvmaeavgidkdkpkeavtvavkmlkddate
kdlsdlvsememmkmigkhkniinllgactqdgplyvivayaskgnlreylrarrppgme
lspdinrvpeeqmtfkdlvsctyqlargmeylasqkcihrdlaarnvlvtennvmkiadf
glardinnidffkettngrlpvkwmapealfdrvythqsdvwsfgvlmweiftlggspyp
gipveelfkllkeghrmdkpanctnelymmmrdcwhavpsqrptfkqlvedldriltltt
neeyldlsq

Sequence, based on observed residues (ATOM records):

>d5eg3a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
felpedpkwefprdkltlgkplgegafgqvvmaeavgidkdkpkeavtvavkmlkddate
kdlsdlvsememmkmigkhkniinllgactqdgplyvivayaskgnlreylrarrppgnr
vpeeqmtfkdlvsctyqlargmeylasqkcihrdlaarnvlvtennvmkiadfglardin
nidffkettngrlpvkwmapealfdrvythqsdvwsfgvlmweiftlggspypgipveel
fkllkeghrmdkpanctnelymmmrdcwhavpsqrptfkqlvedldriltlttneeyldl
sq

Timeline for d5eg3a_:

• d5eg3a_ first appeared in SCOPe 2.06
  
• d5eg3a_ appears in SCOPe 2.07