Lineage for d5egub_ (5egu B:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1993780Fold a.29: Bromodomain-like [47363] (15 superfamilies)
    4 helices; bundle; minor mirror variant of up-and-down topology
  4. 1993781Superfamily a.29.2: Bromodomain [47370] (2 families) (S)
  5. 1993941Family a.29.2.0: automated matches [191428] (1 protein)
    not a true family
  6. 1993942Protein automated matches [190615] (10 species)
    not a true protein
  7. 1993960Species Human (Homo sapiens) [TaxId:9606] [187641] (647 PDB entries)
  8. 1994729Domain d5egub_: 5egu B: [313667]
    Other proteins in same PDB: d5egud2
    automated match to d4hbwa_
    complexed with 5nq, edo

Details for d5egub_

PDB Entry: 5egu (more details), 2.21 Å

PDB Description: first domain of human bromodomain brd4 in complex with inhibitor 3- butyl-8-(6-butyl-5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2- ylsulfanylmethyl)-7-ethyl-3,7-dihydropurine-2,6-dione
PDB Compounds: (B:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d5egub_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5egub_ a.29.2.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d5egub_:

Click to download the PDB-style file with coordinates for d5egub_.
(The format of our PDB-style files is described here.)

Timeline for d5egub_: