SCOPe 2.08: Domain d5edgd1: 5edg D:457-768

Lineage for d5edgd1 (5edg D:457-768)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (9 families)

5. Family a.211.1.0: automated matches [191566] (1 protein)
   not a true family

6. Protein automated matches [190983] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188676] (139 PDB entries)

8. Domain d5edgd1: 5edg D:457-768 [313659]
   Other proteins in same PDB: d5edgb2, d5edgd2
   automated match to d5axqb_
   complexed with 5mg, mg, zn

Details for d5edgd1

PDB Entry: 5edg, 2.3 Å

PDB Description: human pde10a in complex with 3-(2-chloro-5-phenyl-3h-imidazol-4-yl)-1- (3-trifluoromethoxy-phenyl)-1h-pyridazin-4-one at 2.30a

PDB Compounds: (D:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d5edgd1:

Sequence; same for both SEQRES and ATOM records:

>d5edgd1 a.211.1.0 (D:457-768) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qglmqftlpvrlcreielfhfdigpfenmwpgifvymvhrscgtscfeleklcrfimsvk
knyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhrgfsnsylq
kfdhplaalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdla
lyfgnrkqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvtkltandiyaef
waegdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilpptepllkacr
dnlsqwekvirg

Timeline for d5edgd1:

• d5edgd1 first appeared in SCOPe 2.06
  
• d5edgd1 appears in SCOPe 2.07