Lineage for d4yt1a_ (4yt1 A:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2335122Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 2335123Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families) (S)
  5. 2335124Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)
  6. 2335636Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)
  7. 2335637Species Human (Homo sapiens) [TaxId:9606] [48525] (132 PDB entries)
    Uniprot P37231 232-505
  8. 2335750Domain d4yt1a_: 4yt1 A: [312180]
    automated match to d3prga_
    complexed with jjb

Details for d4yt1a_

PDB Entry: 4yt1 (more details), 2.2 Å

PDB Description: human ppar gamma ligand binding domain in complex with a gammma selective synthetic partial agonist mekt76
PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d4yt1a_:

Sequence, based on SEQRES records: (download)

>d4yt1a_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
npesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikf
khitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvhe
iiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdl
aifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrq
ivtehvqllqvikktetdmslhpllqeiykdl

Sequence, based on observed residues (ATOM records): (download)

>d4yt1a_ a.123.1.1 (A:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
npesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikk
evairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmn
kdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsg
drpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqv
ikktetdmslhpllqeiykdl

SCOPe Domain Coordinates for d4yt1a_:

Click to download the PDB-style file with coordinates for d4yt1a_.
(The format of our PDB-style files is described here.)

Timeline for d4yt1a_: