SCOPe 2.08: Domain d4ybka_: 4ybk A:

Lineage for d4ybka_ (4ybk A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein c-src tyrosine kinase [56155] (3 species)
   PTK group; Src subfamily; non-membrane spanning protein tyrosine kinase

7. Species Chicken (Gallus gallus) [TaxId:9031] [56157] (56 PDB entries)

8. Domain d4ybka_: 4ybk A: [312167]
   automated match to d3f6xa_
   complexed with 4b7

Details for d4ybka_

PDB Entry: 4ybk, 2.5 Å

PDB Description: c-helix-out dasatinib analog crystallized with c-src kinase

PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase Src

SCOPe Domain Sequences for d4ybka_:

Sequence, based on SEQRES records:

>d4ybka_ d.144.1.7 (A:) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
akdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmk
klrheklvqlyavvseepiyivteymskgslldflkgemgkylrlpqlvdmaaqiasgma
yvermnyvhrdlraanilvgenlvckvadfglarliedneytarqgakfpikwtapeaal
ygrftiksdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlm
cqcwrkdpeerptfeylqafledyftstepqyqpgenl

Sequence, based on observed residues (ATOM records):

>d4ybka_ d.144.1.7 (A:) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
akdaweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmk
klrheklvqlyavvseepiyivteymskgslldflkgemgkylrlpqlvdmaaqiasgma
yvermnyvhrdlraanilvgenlvckvadfglarlkfpikwtapeaalygrftiksdvws
fgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrkdpeerp
tfeylqafledyftstepqyqpgenl

Timeline for d4ybka_:

• d4ybka_ first appeared in SCOPe 2.06
  
• d4ybka_ appears in SCOPe 2.07