SCOPe 2.07: Domain d4y4ld_: 4y4l D:

Lineage for d4y4ld_ (4y4l D:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
   core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander

4. Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (9 families)

5. Family c.3.1.6: Thi4-like [141942] (2 proteins)
   Pfam PF01946; stand-alone, moderately decorated domain

6. Protein Thiazole biosynthetic enzyme Thi4 [141943] (2 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [141944] (2 PDB entries)
   Uniprot P32318 16-326
   mitochondrial

8. Domain d4y4ld_: 4y4l D: [312070]
   automated match to d2gjcb_
   complexed with 48n

Details for d4y4ld_

PDB Entry: 4y4l, 2 Å

PDB Description: crystal structure of yeast thi4-c205s

PDB Compounds: (D:) Thiamine thiazole synthase

SCOPe Domain Sequences for d4y4ld_:

Sequence, based on SEQRES records:

>d4y4ld_ c.3.1.6 (D:) Thiazole biosynthetic enzyme Thi4 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
vthclsdivkkedwsdfkfapirestvsramtsryfkdldkfavsdviivgagssglsaa
yviaknrpdlkvciiessvapgggswlggqlfsamvmrkpahlflqeleipyedegdyvv
vkhaalfistvlskvlqlpnvklfnatcvedlvtrpptekgevtvagvvtnwtlvtqahg
tqcsmdpnvielagykndgtrdlsqkhgvilsttghdgpfgafcakrivdidqnqklggm
kgldmnhaehdvvihsgayagvdnmyfagmevaeldglnrmgptfgamalsgvhaaeqil
khfa

Sequence, based on observed residues (ATOM records):

>d4y4ld_ c.3.1.6 (D:) Thiazole biosynthetic enzyme Thi4 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
vthclsdivkkedwsdfkfapirestvsramtsryfkdldkfavsdviivgagssglsaa
yviaknrpdlkvciiessvapgggswlggqlfsamvmrkpahlflqeleipyedegdyvv
vkhaalfistvlskvlqlpnvklfnatcvedlvtrpptekgevtvagvvtnwtlvtqahg
tcsmdpnvielagykndgtrdlsqkhgvilsttghdgpfgafcakrivdidqnqklggmk
gldmnhaehdvvihsgayagvdnmyfagmevaeldglnrmgptfgamalsgvhaaeqilk
hfa

Timeline for d4y4ld_:

• d4y4ld_ first appeared in SCOPe 2.06
  
• d4y4ld_ appears in the current release, SCOPe 2.08