SCOPe 2.07: Domain d4xr8c_: 4xr8 C:

Lineage for d4xr8c_ (4xr8 C:)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (9 superfamilies)
   sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold

4. Superfamily b.2.5: p53-like transcription factors [49417] (8 families)

5. Family b.2.5.2: p53 DNA-binding domain-like [81314] (3 proteins)

6. Protein p53 tumor suppressor, DNA-binding domain [49419] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [49420] (65 PDB entries)

8. Domain d4xr8c_: 4xr8 C: [311849]
   automated match to d1ycsa_
   complexed with edo, mal, peg, zn

Details for d4xr8c_

PDB Entry: 4xr8, 2.25 Å

PDB Description: crystal structure of the hpv16 e6/e6ap/p53 ternary complex at 2.25 a resolution

PDB Compounds: (C:) Cellular tumor antigen p53

SCOPe Domain Sequences for d4xr8c_:

Sequence; same for both SEQRES and ATOM records:

>d4xr8c_ b.2.5.2 (C:) p53 tumor suppressor, DNA-binding domain {Human (Homo sapiens) [TaxId: 9606]}
sssvpsqktyqgsygfrlgflhsgtaksvtctyspalnkmfcqlaktcpvqlwvdstppp
gtrvramaiykqsqhmtevvrrcphhercsdsdglappqhlirvegnlrveylddrntfr
hsvvvpyeppevgsdcttihynymcnsscmggmnrrpiltiitledssgnllgrnsfevr
vcacpgrdrrteeenlrkk

Timeline for d4xr8c_:

• d4xr8c_ first appeared in SCOPe 2.06
  
• d4xr8c_ appears in the current release, SCOPe 2.08