| Class d: Alpha and beta proteins (a+b) [53931] (388 folds) |
| Fold d.3: Cysteine proteinases [54000] (1 superfamily) consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn |
Superfamily d.3.1: Cysteine proteinases [54001] (24 families) ![]() the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet |
| Family d.3.1.23: Papain-like viral protease catalytic domain [310648] (2 proteins) C-terminal part of Pfam PF08715 |
| Protein automated matches [310868] (6 species) not a true protein |
| Betacoronavirus england 1 [TaxId:1263720] [311420] (1 PDB entry) |
| Domain d4r3da2: 4r3d A:63-326 [309356] Other proteins in same PDB: d4r3da1, d4r3db1 automated match to d4p16a2 complexed with zn |
| Domain d4r3db2: 4r3d B:63-326 [309358] Other proteins in same PDB: d4r3da1, d4r3db1 automated match to d4p16a2 complexed with zn |
| Human coronavirus emc [TaxId:1263720] [311464] (1 PDB entry) |
| Domain d4wura2: 4wur A:62-319 [301220] Other proteins in same PDB: d4wura1, d4wurb_ automated match to d4p16a2 complexed with ipa, zn |
| Human sars coronavirus [TaxId:227859] [333837] (3 PDB entries) |
| Domain d5tl6b2: 5tl6 B:63-316 [333841] Other proteins in same PDB: d5tl6a_, d5tl6b1, d5tl6c_, d5tl6d1 automated match to d2fe8a2 complexed with so4, zn |
| Domain d5tl6d2: 5tl6 D:63-316 [333838] Other proteins in same PDB: d5tl6a_, d5tl6b1, d5tl6c_, d5tl6d1 automated match to d2fe8a2 complexed with so4, zn |
| Domain d5y3ea2: 5y3e A:63-315 [348688] Other proteins in same PDB: d5y3ea1, d5y3ea3 automated match to d2fe8a2 complexed with gol, na, zn |
| Domain d5y3qa2: 5y3q A:63-315 [348676] Other proteins in same PDB: d5y3qa1, d5y3qa3 automated match to d2fe8a2 complexed with bme, gol, na, zn |
| SARS coronavirus [TaxId:227859] [311282] (4 PDB entries) |
| Domain d3e9sa2: 3e9s A:63-315 [305253] Other proteins in same PDB: d3e9sa1, d3e9sa3 automated match to d2fe8a2 complexed with cl, ttt, zn |
| Domain d4m0wa2: 4m0w A:63-319 [299381] Other proteins in same PDB: d4m0wa1, d4m0wb_ automated match to d2fe8a2 complexed with gol, na, nhe, zn; mutant |
| Domain d4mm3b2: 4mm3 B:63-316 [299532] Other proteins in same PDB: d4mm3a_, d4mm3b1, d4mm3b3 automated match to d2fe8a2 complexed with zn |
| Domain d5tl7b2: 5tl7 B:63-316 [333881] Other proteins in same PDB: d5tl7a_, d5tl7b1, d5tl7b3, d5tl7c_, d5tl7d1 automated match to d2fe8a2 complexed with zn |
| Domain d5tl7d2: 5tl7 D:63-316 [333892] Other proteins in same PDB: d5tl7a_, d5tl7b1, d5tl7b3, d5tl7c_, d5tl7d1 automated match to d2fe8a2 complexed with zn |
| Sars coronavirus [TaxId:228330] [311412] (2 PDB entries) |
| Domain d4ovza2: 4ovz A:63-313 [307962] Other proteins in same PDB: d4ovza1 automated match to d2fe8a2 complexed with dms, na, p85, zn |
| Domain d4ow0a2: 4ow0 A:63-315 [307964] Other proteins in same PDB: d4ow0a1 automated match to d2fe8a2 complexed with dms, gol, s88, zn |
| Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049] [385225] (32 PDB entries) |
| Domain d6wrha2: 6wrh A:62-315 [385226] Other proteins in same PDB: d6wrha1, d6wrha3 automated match to d4m0wa2 complexed with cl, gol, po4, zn; mutant |
| Domain d6wzua2: 6wzu A:62-315 [386400] Other proteins in same PDB: d6wzua1 automated match to d2fe8a2 complexed with cl, gol, po4, zn |
| Domain d6xa9a2: 6xa9 A:62-314 [388066] Other proteins in same PDB: d6xa9a1, d6xa9b_, d6xa9c1, d6xa9d_, d6xa9e1, d6xa9f_ automated match to d2fe8a2 complexed with gol, zn |
| Domain d6xa9c2: 6xa9 C:62-314 [388046] Other proteins in same PDB: d6xa9a1, d6xa9b_, d6xa9c1, d6xa9d_, d6xa9e1, d6xa9f_ automated match to d2fe8a2 complexed with gol, zn |
| Domain d6xa9e2: 6xa9 E:62-313 [388094] Other proteins in same PDB: d6xa9a1, d6xa9b_, d6xa9c1, d6xa9d_, d6xa9e1, d6xa9f_ automated match to d2fe8a2 complexed with gol, zn |
| Domain d6xaaa2: 6xaa A:62-313 [388048] Other proteins in same PDB: d6xaaa1, d6xaab_ automated match to d2fe8a2 complexed with zn |
| Domain d6xg3a2: 6xg3 A:62-314 [388388] Other proteins in same PDB: d6xg3a1 automated match to d4m0wa2 complexed with cl, po4, zn; mutant |
| Domain d6yvaa2: 6yva A:62-308 [385720] Other proteins in same PDB: d6yvaa1, d6yvac1, d6yvac2 automated match to d4m0wa2 |
| Domain d7cjda2: 7cjd A:62-312 [389947] Other proteins in same PDB: d7cjda1, d7cjdb1, d7cjdc1, d7cjdd1 automated match to d4m0wa2 complexed with edo, zn; mutant |
| Domain d7cjdb2: 7cjd B:62-312 [389971] Other proteins in same PDB: d7cjda1, d7cjdb1, d7cjdc1, d7cjdd1 automated match to d4m0wa2 complexed with edo, zn; mutant |
| Domain d7cjdc2: 7cjd C:62-312 [389962] Other proteins in same PDB: d7cjda1, d7cjdb1, d7cjdc1, d7cjdd1 automated match to d4m0wa2 complexed with edo, zn; mutant |
| Domain d7cjdd2: 7cjd D:62-313 [389934] Other proteins in same PDB: d7cjda1, d7cjdb1, d7cjdc1, d7cjdd1 automated match to d4m0wa2 complexed with edo, zn; mutant |
| Domain d7cmda2: 7cmd A:62-315 [390002] Other proteins in same PDB: d7cmda1, d7cmda3, d7cmdb1, d7cmdb3, d7cmdc1, d7cmdc3, d7cmdd1, d7cmdd3 automated match to d4m0wa2 complexed with ttt, zn |
| Domain d7cmdb2: 7cmd B:62-315 [389993] Other proteins in same PDB: d7cmda1, d7cmda3, d7cmdb1, d7cmdb3, d7cmdc1, d7cmdc3, d7cmdd1, d7cmdd3 automated match to d4m0wa2 complexed with ttt, zn |
| Domain d7cmdc2: 7cmd C:62-314 [390097] Other proteins in same PDB: d7cmda1, d7cmda3, d7cmdb1, d7cmdb3, d7cmdc1, d7cmdc3, d7cmdd1, d7cmdd3 automated match to d4m0wa2 complexed with ttt, zn |
| Domain d7cmdd2: 7cmd D:62-315 [390026] Other proteins in same PDB: d7cmda1, d7cmda3, d7cmdb1, d7cmdb3, d7cmdc1, d7cmdc3, d7cmdd1, d7cmdd3 automated match to d4m0wa2 complexed with ttt, zn |
| Domain d7d47a2: 7d47 A:62-316 [390100] Other proteins in same PDB: d7d47a1, d7d47b1 automated match to d4m0wa2 complexed with ca, zn |
| Domain d7d47b2: 7d47 B:62-315 [390090] Other proteins in same PDB: d7d47a1, d7d47b1 automated match to d4m0wa2 complexed with ca, zn |
| Domain d7d6ha2: 7d6h A:63-316 [394516] Other proteins in same PDB: d7d6ha1 automated match to d4m0wa2 complexed with po4, zn; mutant |
| Domain d7d7ka2: 7d7k A:62-315 [403183] Other proteins in same PDB: d7d7ka1, d7d7kb1 automated match to d4m0wa2 complexed with cff, edo, so4, zn |
| Domain d7d7kb2: 7d7k B:62-315 [403286] Other proteins in same PDB: d7d7ka1, d7d7kb1 automated match to d4m0wa2 complexed with cff, edo, so4, zn |
| Domain d7d7la2: 7d7l A:62-315 [403209] Other proteins in same PDB: d7d7la1, d7d7lb1 automated match to d4m0wa2 complexed with cff, gol, gxu, so4, zn |
| Domain d7d7lb2: 7d7l B:62-315 [403215] Other proteins in same PDB: d7d7la1, d7d7lb1 automated match to d4m0wa2 complexed with cff, gol, gxu, so4, zn |
| Domain d7d7ta2: 7d7t A:63-316 [394501] Other proteins in same PDB: d7d7ta1, d7d7tb1 automated match to d4m0wa2 complexed with gyx, zn; mutant |
| Domain d7d7tb2: 7d7t B:63-316 [394497] Other proteins in same PDB: d7d7ta1, d7d7tb1 automated match to d4m0wa2 complexed with gyx, zn; mutant |
| Domain d7e35a2: 7e35 A:63-316 [401980] Other proteins in same PDB: d7e35a1 automated match to d4m0wa2 complexed with gyx, zn; mutant |
| Domain d7e35b1: 7e35 B:63-316 [401981] Other proteins in same PDB: d7e35a1 automated match to d4m0wa2 complexed with gyx, zn; mutant |
| Domain d7jira2: 7jir A:62-314 [390285] Other proteins in same PDB: d7jira1 automated match to d4m0wa2 complexed with act, cl, mes, ttt, zn; mutant |
| Domain d7jita2: 7jit A:62-315 [390200] Other proteins in same PDB: d7jita1 automated match to d4m0wa2 complexed with act, cl, mes, y95, zn; mutant |
| Domain d7jiva2: 7jiv A:62-315 [390229] Other proteins in same PDB: d7jiva1 automated match to d4m0wa2 complexed with act, cl, mes, vby, zn; mutant |
| Domain d7jiwa2: 7jiw A:62-315 [390174] Other proteins in same PDB: d7jiwa1 automated match to d2fe8a2 complexed with cl, mes, vby, zn |
| Domain d7jn2a2: 7jn2 A:62-315 [390276] Other proteins in same PDB: d7jn2a1 automated match to d2fe8a2 complexed with act, cl, unx, y41, zn |
| Domain d7jrna2: 7jrn A:62-315 [390295] Other proteins in same PDB: d7jrna1, d7jrnj1 automated match to d2fe8a2 complexed with so4, ttt, zn |
| Domain d7jrnj2: 7jrn J:62-315 [390299] Other proteins in same PDB: d7jrna1, d7jrnj1 automated match to d2fe8a2 complexed with so4, ttt, zn |
| Domain d7koja2: 7koj A:62-314 [395000] Other proteins in same PDB: d7koja1 automated match to d4m0wa2 complexed with act, cl, mes, unx, y94, zn; mutant |
| Domain d7koka2: 7kok A:62-314 [395075] Other proteins in same PDB: d7koka1 automated match to d4m0wa2 complexed with act, cl, mes, unx, y96, zn; mutant |
| Domain d7kola2: 7kol A:62-314 [394939] Other proteins in same PDB: d7kola1 automated match to d2fe8a2 complexed with cl, mes, y96, zn |
| Domain d7krxa2: 7krx A:62-314 [395126] Other proteins in same PDB: d7krxa1 automated match to d4m0wa2 complexed with act, cl, unx, y41, zn; mutant |
| Domain d7lbra2: 7lbr A:62-315 [399508] Other proteins in same PDB: d7lbra1, d7lbra3, d7lbrb1, d7lbrb3 automated match to d2fe8a2 complexed with gol, so4, xt7, zn |
| Domain d7lbrb2: 7lbr B:62-315 [399496] Other proteins in same PDB: d7lbra1, d7lbra3, d7lbrb1, d7lbrb3 automated match to d2fe8a2 complexed with gol, so4, xt7, zn |
| Domain d7lbsa2: 7lbs A:62-315 [399473] Other proteins in same PDB: d7lbsa1, d7lbsa3, d7lbsb1, d7lbsb3 automated match to d2fe8a2 complexed with bo3, gol, so4, xr8, zn |
| Domain d7lbsb2: 7lbs B:62-315 [399493] Other proteins in same PDB: d7lbsa1, d7lbsa3, d7lbsb1, d7lbsb3 automated match to d2fe8a2 complexed with bo3, gol, so4, xr8, zn |
| Domain d7llfa2: 7llf A:62-315 [399949] Other proteins in same PDB: d7llfa1, d7llfa3, d7llfb1, d7llfb3 automated match to d2fe8a2 complexed with bo3, gol, so4, y54, zn |
| Domain d7llfb2: 7llf B:62-315 [399915] Other proteins in same PDB: d7llfa1, d7llfa3, d7llfb1, d7llfb3 automated match to d2fe8a2 complexed with bo3, gol, so4, y54, zn |
| Domain d7llza2: 7llz A:62-315 [399909] Other proteins in same PDB: d7llza1, d7llza3, d7llzb1, d7llzb3 automated match to d2fe8a2 complexed with so4, y61, zn |
| Domain d7llzb2: 7llz B:62-315 [399821] Other proteins in same PDB: d7llza1, d7llza3, d7llzb1, d7llzb3 automated match to d2fe8a2 complexed with so4, y61, zn |
| Domain d7losa2: 7los A:62-315 [399865] Other proteins in same PDB: d7losa1, d7losa3, d7losb1, d7losb3 automated match to d2fe8a2 complexed with cl, so4, y97, zn |
| Domain d7losb2: 7los B:62-315 [399741] Other proteins in same PDB: d7losa1, d7losa3, d7losb1, d7losb3 automated match to d2fe8a2 complexed with cl, so4, y97, zn |
| Domain d7m1ya2: 7m1y A:62-315 [402370] Other proteins in same PDB: d7m1ya1, d7m1yb1 automated match to d4m0wa2 complexed with 9jt, cl, fmt, gol, iod, na, zn; mutant |
| Domain d7m1yb2: 7m1y B:62-314 [402364] Other proteins in same PDB: d7m1ya1, d7m1yb1 automated match to d4m0wa2 complexed with 9jt, cl, fmt, gol, iod, na, zn; mutant |
| Domain d7ofsa2: 7ofs A:62-315 [403826] Other proteins in same PDB: d7ofsa1 automated match to d2fe8a2 complexed with cl, yrl, zn |
| Domain d7ofta2: 7oft A:62-315 [403821] Other proteins in same PDB: d7ofta1 automated match to d2fe8a2 complexed with cl, hba, zn |
Timeline for Protein automated matches from d.3.1.23: Papain-like viral protease catalytic domain: