SCOPe 2.07: Protein: Papain-like protease PLpro, catalytic domain

Lineage for Protein: Papain-like protease PLpro, catalytic domain

Root: SCOPe 2.07
Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
Fold d.3: Cysteine proteinases [54000] (1 superfamily)
consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

Superfamily d.3.1: Cysteine proteinases [54001] (24 families)

(S)

the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

Family d.3.1.23: Papain-like viral protease catalytic domain [310648] (2 protein domains)
C-terminal part of Pfam PF08715
Protein Papain-like protease PLpro, catalytic domain [310795] (3 species)

Species:

Human betacoronavirus 2c EMC/2012 [TaxId:1235996] [311055] (5 PDB entries)
1. Domain for 4p16:
  - Domain d4p16a2: 4p16 A:62-319 [307968]
    Other proteins in same PDB: d4p16a1
    complexed with zn
2. Domain for 4pt5:
  - Domain d4pt5a2: 4pt5 A:64-324 [308009]
    Other proteins in same PDB: d4pt5a1
    automated match to d4p16a2
    complexed with zn
3. Domain for 4rna:
  - Domain d4rnaa2: 4rna A:62-322 [309477]
    Other proteins in same PDB: d4rnaa1
    automated match to d4p16a2
    complexed with po4, zn
4. Domain for 5v69:
  - Domain d5v69a2: 5v69 A:1543-1802 [334684]
    Other proteins in same PDB: d5v69a1, d5v69b_
    automated match to d4pt5a2
    complexed with cl, na, pgo, zn
5. Domain for 5v6a:
  - Domain d5v6aa2: 5v6a A:1543-1800 [334340]
    Other proteins in same PDB: d5v6aa1, d5v6ab_
    automated match to d4pt5a2
    complexed with cl, flc, zn
Human betacoronavirus 2c jordan-n3/2012 [TaxId:1306931] [311427] (5 PDB entries)
1. Domain for 4rez:
  - Domain d4reza2: 4rez A:1543-1803 [309422]
    Other proteins in same PDB: d4reza1
    automated match to d4p16a2
    complexed with pgo, zn
2. Domain for 4rf0:
  - Domain d4rf0a2: 4rf0 A:1543-1801 [300657]
    Other proteins in same PDB: d4rf0a1, d4rf0b_
    automated match to d4p16a2
    complexed with 3cn, so4, zn
3. Domain for 4rf1:
  - Domain d4rf1a2: 4rf1 A:1543-1803 [300659]
    Other proteins in same PDB: d4rf1a1, d4rf1b_
    automated match to d4p16a2
    complexed with 3cn, pgo, zn
4. Domains for 5w8t:
  1. Domain d5w8ta2: 5w8t A:62-320 [339684]
    Other proteins in same PDB: d5w8ta1, d5w8tb_, d5w8tc1, d5w8td_
    automated match to d4pt5a2
    complexed with aye, mpd, zn
  2. Domain d5w8tc2: 5w8t C:62-320 [339686]
    Other proteins in same PDB: d5w8ta1, d5w8tb_, d5w8tc1, d5w8td_
    automated match to d4pt5a2
    complexed with aye, mpd, zn
5. Domains for 5w8u:
  1. Domain d5w8ua2: 5w8u A:62-320 [339689]
    Other proteins in same PDB: d5w8ua1, d5w8ub_, d5w8uc1, d5w8ud_
    automated match to d4pt5a2
    complexed with aye, mpd, zn
  2. Domain d5w8uc2: 5w8u C:62-320 [339682]
    Other proteins in same PDB: d5w8ua1, d5w8ub_, d5w8uc1, d5w8ud_
    automated match to d4pt5a2
    complexed with aye, mpd, zn
SARS coronavirus [TaxId:227859] [311054] (1 PDB entry)
- Domains for 2fe8:
  1. Domain d2fe8a2: 2fe8 A:63-315 [303816]
    Other proteins in same PDB: d2fe8a1, d2fe8b1, d2fe8c1
    complexed with br, so4, zn
  2. Domain d2fe8b2: 2fe8 B:63-314 [303818]
    Other proteins in same PDB: d2fe8a1, d2fe8b1, d2fe8c1
    complexed with br, so4, zn
  3. Domain d2fe8c2: 2fe8 C:63-313 [303820]
    Other proteins in same PDB: d2fe8a1, d2fe8b1, d2fe8c1
    complexed with br, so4, zn

More info for Protein Papain-like protease PLpro, catalytic domain from d.3.1.23: Papain-like viral protease catalytic domain

Timeline for Protein Papain-like protease PLpro, catalytic domain from d.3.1.23: Papain-like viral protease catalytic domain:

Protein Papain-like protease PLpro, catalytic domain from d.3.1.23: Papain-like viral protease catalytic domain first appeared in SCOPe 2.06