Lineage for Protein: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2459390Fold c.50: Macro domain-like [52948] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 6 strands, order 165243, strand 3 is antiparallel to the rest
  4. 2459391Superfamily c.50.1: Macro domain-like [52949] (4 families) (S)
  5. 2459514Family c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like [310642] (2 protein domains)
    Pfam PF05028
    Contains N- and C-terminal extensions to macrodomain, including Tyr clasp, discussed in PubMed 22609859
  6. 2459515Protein Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain [310785] (3 species)

Species:

  1. 2459516Human (Homo sapiens) [TaxId:9606] [324080] (1 PDB entry)
  2. 2459518Mouse (Mus musculus) [TaxId:10090] [311376] (7 PDB entries)
    1. Domains for 4fc2:
      1. 2459519Domain d4fc2a_: 4fc2 A: [307353]
        automated match to d3ueka_
        complexed with so4
      2. 2459520Domain d4fc2b_: 4fc2 B: [307354]
        automated match to d3ueka_
        complexed with so4
      3. 2459521Domain d4fc2c_: 4fc2 C: [307355]
        automated match to d3ueka_
        complexed with so4
      4. 2459522Domain d4fc2d_: 4fc2 D: [307356]
        automated match to d3ueka_
        complexed with so4
    2. Domain for 4n9y:
    3. Domains for 4n9z:
      1. 2459523Domain d4n9za_: 4n9z A: [307755]
        automated match to d3ueka_
        complexed with so4, v3l; mutant
      2. 2459524Domain d4n9zb_: 4n9z B: [307756]
        automated match to d3ueka_
        complexed with so4, v3l; mutant
    4. Domains for 4na0:
      1. 2459532Domain d4na0a_: 4na0 A: [307757]
        automated match to d3ueka_
        complexed with ar6, iod
      2. 2459533Domain d4na0b_: 4na0 B: [307758]
        automated match to d3ueka_
        complexed with ar6, iod
      3. 2459534Domain d4na0c_: 4na0 C: [307759]
        automated match to d3ueka_
        complexed with ar6, iod
    5. Domains for 4na4:
      1. 2459529Domain d4na4a_: 4na4 A: [307760]
        automated match to d3ueka_
        complexed with a1r, iod
      2. 2459530Domain d4na4b_: 4na4 B: [307761]
        automated match to d3ueka_
        complexed with a1r, iod
      3. 2459531Domain d4na4c_: 4na4 C: [307762]
        automated match to d3ueka_
        complexed with a1r, iod
    6. Domain for 4na5:
    7. Domains for 4na6:
      1. 2459527Domain d4na6a_: 4na6 A: [307764]
        automated match to d3ueka_
        complexed with so4; mutant
      2. 2459528Domain d4na6b_: 4na6 B: [307765]
        automated match to d3ueka_
        complexed with so4; mutant
  3. 2459535Norway rat (Rattus norvegicus) [TaxId:10116] [311041] (2 PDB entries)
    1. Domain for 3uek:
    2. Domains for 3uel:
      1. 2459537Domain d3uela_: 3uel A: [306651]
        automated match to d3ueka_
        complexed with a1r
      2. 2459538Domain d3uelb_: 3uel B: [306652]
        automated match to d3ueka_
        complexed with a1r
      3. 2459539Domain d3uelc_: 3uel C: [306653]
        automated match to d3ueka_
        complexed with a1r

More info for Protein Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain from c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like

Timeline for Protein Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain from c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like:

  • Protein Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain from c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like first appeared in SCOPe 2.06