SCOPe 2.08: Domain d5ffma2: 5ffm A:325-621

Lineage for d5ffma2 (5ffm A:325-621)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.14: RNA helicase [52724] (7 proteins)
   duplication: consists of two similar domains, one binds NTP and the other binds RNA; also contains an all-alpha subdomain in the C-terminal extension

6. Protein YFV helicase, C-terminal domain [418965] (1 species)

7. Species Yellow fever virus [TaxId:11089] [419427] (2 PDB entries)
   Uniprot P19901

8. Domain d5ffma2: 5ffm A:325-621 [310541]
   Other proteins in same PDB: d5ffma1, d5ffma3
   has additional subdomain(s) that are not in the common domain

Details for d5ffma2

PDB Entry: 5ffm, 2.6 Å

PDB Description: yellow fever virus helicase

PDB Compounds: (A:) Serine protease NS3

SCOPe Domain Sequences for d5ffma2:

Sequence, based on SEQRES records:

>d5ffma2 c.37.1.14 (A:325-621) YFV helicase, C-terminal domain {Yellow fever virus [TaxId: 11089]}
gtsdefphsngeiedvqtdipsepwntghdwiladkrptawflpsiraanvmaaslrkag
ksvvvlnrktfereyptikqkkpdfilatdiaemganlcvervldcrtafkpvlvdegrk
vaikgplrisassaaqrrgrigrnpnrdgdsyyyseptsennahhvcwleasmlldnmev
rggmvaplygvegtktpvspgemrlrddqrkvfrelvrncdlpvwlswqvakaglktndr
kwcfegpeeheilndsgetvkcrapggakkplrprwcdervssdqsalsefikfaeg

Sequence, based on observed residues (ATOM records):

>d5ffma2 c.37.1.14 (A:325-621) YFV helicase, C-terminal domain {Yellow fever virus [TaxId: 11089]}
gtsdefphsngeiedvqtdipsepwntghdwiladkrptawflpsiraanvmaaslrkag
ksvvvlnrkkpdfilatdiaemganlcvervldcrtafkpvlvdegrkvaikgplrisas
saaqrrgrigrnpnrdgdsyyyseptsennahhvcwleasmlldnmevrggmvaplygve
gtktpvspgemrlrddqrkvfrelvrncdlpvwlswqvakaglktndrkwcfegpeehei
lndsgetvkcrapggakkplrprwcdervssdqsalsefikfaeg

Timeline for d5ffma2:

• d5ffma2 first appeared in SCOPe 2.06
  
• d5ffma2 appears in SCOPe 2.07