Lineage for d5eqyb_ (5eqy B:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2984698Family d.144.1.8: Choline kinase [90040] (2 proteins)
    Pfam PF02958
  6. 2984699Protein Choline kinase [90041] (2 species)
  7. 2984700Species Human (Homo sapiens) [TaxId:9606] [311002] (13 PDB entries)
  8. 2984724Domain d5eqyb_: 5eqy B: [310526]
    automated match to d2i7qa_
    complexed with 5ra

Details for d5eqyb_

PDB Entry: 5eqy (more details), 2.5 Å

PDB Description: crystal structure of choline kinase alpha-1 bound by 5-[(4-methyl-1,4- diazepan-1-yl)methyl]-2-[4-[(4-methyl-1,4-diazepan-1-yl) methyl]phenyl]benzenecarbonitrile (compound 65)
PDB Compounds: (B:) choline kinase alpha

SCOPe Domain Sequences for d5eqyb_:

Sequence, based on SEQRES records: (download)

>d5eqyb_ d.144.1.8 (B:) Choline kinase {Human (Homo sapiens) [TaxId: 9606]}
qpeprtrrraylwckeflpgawrglredefhisvirgglsnmlfqcslpdttatlgdepr
kvllrlygailqmrscnkegseqaqkenefqgaeamvlesvmfailaerslgpklygifp
qgrleqfipsrrldteelslpdisaeiaekmatfhgmkmpfnkepkwlfgtmekylkevl
rikfteesrikklhkllsynlplelenlrsllestpspvvfchndcqegnilllegrens
ekqklmlidfeyssynyrgfdignhfcewmydysyekypffranirkyptkkqqlhfiss
ylpafqndfenlsteeksiikeemllevnrfalashflwglwsivqakissiefgymdya
qarfdayfhqkrklgv

Sequence, based on observed residues (ATOM records): (download)

>d5eqyb_ d.144.1.8 (B:) Choline kinase {Human (Homo sapiens) [TaxId: 9606]}
qpeprtrrraylwckeflpgawrglredefhisvirgglsnmlfqcslpdttatlgdepr
kvllrlygaamvlesvmfailaerslgpklygifpqgrleqfipsrrldteelslpdisa
eiaekmatfhgmkmpfnkepkwlfgtmekylkevlrikfteesrikklhkllsynlplel
enlrsllestpspvvfchndcqegnilllegrensekqklmlidfeyssynyrgfdignh
fcewmydysyekypffranirkyptkkqqlhfissylpafqndfenlsteeksiikeeml
levnrfalashflwglwsivqakissiefgymdyaqarfdayfhqkrklgv

SCOPe Domain Coordinates for d5eqyb_:

Click to download the PDB-style file with coordinates for d5eqyb_.
(The format of our PDB-style files is described here.)

Timeline for d5eqyb_: