Lineage for d5d7pa1 (5d7p A:56-355)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2444630Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2444631Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2444911Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 proteins)
    silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
  6. 2444971Protein Sirt2 histone deacetylase [63987] (1 species)
  7. 2444972Species Human (Homo sapiens) [TaxId:9606] [63988] (20 PDB entries)
  8. 2444983Domain d5d7pa1: 5d7p A:56-355 [310392]
    Other proteins in same PDB: d5d7pa2
    automated match to d5dy4a_
    complexed with ar6, ocz, peg, zn

Details for d5d7pa1

PDB Entry: 5d7p (more details), 1.76 Å

PDB Description: crystal structure of human sirt2 in complex with adpr and ex-243
PDB Compounds: (A:) nad-dependent protein deacetylase sirtuin-2

SCOPe Domain Sequences for d5d7pa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d5d7pa1 c.31.1.5 (A:56-355) Sirt2 histone deacetylase {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d5d7pa1:

Click to download the PDB-style file with coordinates for d5d7pa1.
(The format of our PDB-style files is described here.)

Timeline for d5d7pa1:

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