SCOPe 2.08: Domain d5d7oa_: 5d7o A:

Lineage for d5d7oa_ (5d7o A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like

4. Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families)
   binds cofactor molecules in the opposite direction than classical Rossmann fold

5. Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 proteins)
   silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain

6. Protein Sirt2 histone deacetylase [63987] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63988] (23 PDB entries)

8. Domain d5d7oa_: 5d7o A: [310390]
   automated match to d5dy4a_
   complexed with ar6, pge, zn

Details for d5d7oa_

PDB Entry: 5d7o, 1.63 Å

PDB Description: crystal structure of sirt2-adpr at an improved resolution

PDB Compounds: (A:) nad-dependent protein deacetylase sirtuin-2

SCOPe Domain Sequences for d5d7oa_:

Sequence; same for both SEQRES and ATOM records:

>d5d7oa_ c.31.1.5 (A:) Sirt2 histone deacetylase {Human (Homo sapiens) [TaxId: 9606]}
rlldeltlegvarymqsercrrviclvgagistsagipdfrspstglydnlekyhlpype
aifeisyfkkhpepffalakelypgqfkptichyfmrllkdkglllrcytqnidtleria
gleqedlveahgtfytshcvsascrheyplswmkekifsevtpkcedcqslvkpdivffg
eslparffscmqsdflkvdlllvmgtslqvqpfasliskaplstprllinkekagqsdpf
lgmimglgggmdfdskkayrdvawlgecdqgclalaellgwkkeledlvrrehasidaq

Timeline for d5d7oa_:

• d5d7oa_ first appeared in SCOPe 2.06
  
• d5d7oa_ appears in SCOPe 2.07