SCOPe 2.08: Domain d5afvb_: 5afv B:

Lineage for d5afvb_ (5afv B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.8: Choline kinase [90040] (2 proteins)
   Pfam PF02958

6. Protein automated matches [310849] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [311202] (11 PDB entries)

8. Domain d5afvb_: 5afv B: [310157]
   automated match to d2i7qa_
   complexed with edo, jh5

Details for d5afvb_

PDB Entry: 5afv, 2.25 Å

PDB Description: pharmacophore-based virtual screening to discover new active compounds for human choline kinase alpha1.

PDB Compounds: (B:) choline kinase alpha

SCOPe Domain Sequences for d5afvb_:

Sequence, based on SEQRES records:

>d5afvb_ d.144.1.8 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
deqpeprtrrraylwckeflpgawrglredefhisvirgglsnmlfqcslpdttatlgde
prkvllrlygailqmrscnkegseqaqkenefqgaeamvlesvmfailaerslgpklygi
fpqgrleqfipsrrldteelslpdisaeiaekmatfhgmkmpfnkepkwlfgtmekylke
vlrikfteesrikklhkllsynlplelenlrsllestpspvvfchndcqegnilllegre
nsekqklmlidfeyssynyrgfdignhfcewmydysyekypffranirkyptkkqqlhfi
ssylpafqndfenlsteeksiikeemllevnrfalashflwglwsivqakissiefgymd
yaqarfdayfhqkrklgv

Sequence, based on observed residues (ATOM records):

>d5afvb_ d.144.1.8 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
deqpeprtrrraylwckeflpgawrglredefhisvirgglsnmlfqcslpdttatlgde
prkvllrlygaeamvlesvmfailaerslgpklygifpqgrleqfipsrrldteelslpd
isaeiaekmatfhgmkmpfnkepkwlfgtmekylkevlrikfteesrikklhkllsynlp
lelenlrsllestpspvvfchndcqegnilllegrensekqklmlidfeyssynyrgfdi
gnhfcewmydysyekypffranirkyptkkqqlhfissylpafqndfenlsteeksiike
emllevnrfalashflwglwsivqakissiefgymdyaqarfdayfhqkrklgv

Timeline for d5afvb_:

• d5afvb_ first appeared in SCOPe 2.06
  
• d5afvb_ appears in SCOPe 2.07