Lineage for d4y6qc_ (4y6q C:)

  1. Root: SCOPe 2.06
  2. 2089713Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2121033Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2121034Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2121318Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (8 proteins)
    silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
  6. 2121386Protein automated matches [191258] (3 species)
    not a true protein
  7. 2121396Species Human (Homo sapiens) [TaxId:9606] [189817] (16 PDB entries)
  8. 2121420Domain d4y6qc_: 4y6q C: [310102]
    automated match to d1j8fc_
    complexed with omr, zn

Details for d4y6qc_

PDB Entry: 4y6q (more details), 1.9 Å

PDB Description: human sirt2 in complex with 2-o-myristoyl-adp-ribose
PDB Compounds: (C:) nad-dependent protein deacetylase sirtuin-2

SCOPe Domain Sequences for d4y6qc_:

Sequence, based on SEQRES records: (download)

>d4y6qc_ c.31.1.5 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
erlldeltlegvarymqsercrrviclvgagistsagipdfrspstglydnlekyhlpyp
eaifeisyfkkhpepffalakelypgqfkptichyfmrllkdkglllrcytqnidtleri
agleqedlveahgtfytshcvsascrheyplswmkekifsevtpkcedcqslvkpdivff
geslparffscmqsdflkvdlllvmgtslqvqpfasliskaplstprllinkekaggggm
dfdskkayrdvawlgecdqgclalaellgwkkeledlvrrehasida

Sequence, based on observed residues (ATOM records): (download)

>d4y6qc_ c.31.1.5 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
erlldeltlegvarymqsercrrviclvgagistsagipdfrspstglydnlekyhlpyp
eaifeisyfkkhpepffalakelypgqfkptichyfmrllkdkglllrcytqnidtleri
agleqedlveahgtfytshcvsascrheyplswmkekifsevtpkcedcqslvkpdivff
geslparffscmqsdflkvdlllvmgtslqvqpfasliskaplstprllinkekagggmd
fdskkayrdvawlgecdqgclalaellgwkkeledlvrrehasida

SCOPe Domain Coordinates for d4y6qc_:

Click to download the PDB-style file with coordinates for d4y6qc_.
(The format of our PDB-style files is described here.)

Timeline for d4y6qc_: