SCOPe 2.06: Domain d4xsdc_: 4xsd C:

Lineage for d4xsdc_ (4xsd C:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein automated matches [190469] (15 species)
   not a true protein

7. Species Varicella-zoster virus (strain oka vaccine) [TaxId:341980] [311478] (3 PDB entries)

8. Domain d4xsdc_: 4xsd C: [310059]
   automated match to d4ez8a_
   complexed with ump

Details for d4xsdc_

PDB Entry: 4xsd, 2.9 Å

PDB Description: complex structure of thymidylate synthase from varicella zoster virus with a dump

PDB Compounds: (C:) Thymidylate synthase

SCOPe Domain Sequences for d4xsdc_:

Sequence, based on SEQRES records:

>d4xsdc_ d.117.1.1 (C:) automated matches {Varicella-zoster virus (strain oka vaccine) [TaxId: 341980]}
tgelqylkqvddilrygvrkrdrtgigtlslfgmqarynlrnefpllttkrvfwravvee
llwfirgstdskelaakdihiwdiygsskflnrngfhkrhtgdlgpiygfqwrhfgaeyk
dcqsnylqqgidqlqtvidtiktnpesrrmiisswnpkdiplmvlppchtlcqfyvange
lscqvyqrsgdmglgvpfniagyalltyivahvtglktgdlihtmgdahiylnhidalkv
qlarspkpfpclkiirnvtdindfkwddfqldgynphppl

Sequence, based on observed residues (ATOM records):

>d4xsdc_ d.117.1.1 (C:) automated matches {Varicella-zoster virus (strain oka vaccine) [TaxId: 341980]}
tgelqylkqvddilrygvrkrdrtgigtlslfgmqarynlrnefpllttkrvfwravvee
llwfirgstdskelaakdihiwdidlgpiygfqwrhfgaeykdcqsnylqqgidqlqtvi
dtiktnpesrrmiisswnpkdiplmvlppchtlcqfyvangelscqvyqrsgdmglgvpf
niagyalltyivahvtglktgdlihtmgdahiylnhidalkvqlarspkpfpclkiirnv
tdindfkwddfqldgynphppl

Timeline for d4xsdc_:

• d4xsdc_ is new in SCOPe 2.06-stable
  
• d4xsdc_ appears in SCOPe 2.07
  
• d4xsdc_ appears in the current release, SCOPe 2.08