Lineage for d1gfw.1 (1gfw A:,B:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2437680Fold c.17: Caspase-like [52128] (1 superfamily)
    3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest
  4. 2437681Superfamily c.17.1: Caspase-like [52129] (3 families) (S)
    mature protein may be composed of two chains folded in a single domain
  5. 2437682Family c.17.1.1: Caspase catalytic domain [52130] (8 protein domains)
  6. 2437683Protein Apopain (caspase-3, cpp32) [52131] (1 species)
  7. 2437684Species Human (Homo sapiens) [TaxId:9606] [52132] (28 PDB entries)
  8. 2437718Domain d1gfw.1: 1gfw A:,B: [30995]
    complexed with msi

Details for d1gfw.1

PDB Entry: 1gfw (more details), 2.8 Å

PDB Description: the 2.8 angstrom crystal structure of caspase-3 (apopain or cpp32)in complex with an isatin sulfonamide inhibitor.
PDB Compounds: (A:) caspase-3 (apopain, p20), (B:) caspase-3 (apopain, p10)

SCOPe Domain Sequences for d1gfw.1:

Sequence; same for both SEQRES and ATOM records: (download)

>g1gfw.1 c.17.1.1 (A:,B:) Apopain (caspase-3, cpp32) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1gfw.1:

Click to download the PDB-style file with coordinates for d1gfw.1.
(The format of our PDB-style files is described here.)

Timeline for d1gfw.1: