Lineage for d4twxa_ (4twx A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2057856Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (5 protein domains)
  6. 2057913Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) [74979] (6 species)
    contains an extra alpha-helical domain
  7. 2057935Species SARS coronavirus [TaxId:227859] [89349] (71 PDB entries)
  8. 2058004Domain d4twxa_: 4twx A: [309674]
    automated match to d1z1ja_
    complexed with 3a4

Details for d4twxa_

PDB Entry: 4twx (more details), 1.89 Å

PDB Description: Structure of SARS-3CL protease complex with a phenylbenzoyl (R,S)-N-decalin type inhibitor
PDB Compounds: (A:) Replicase polyprotein 1ab

SCOPe Domain Sequences for d4twxa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4twxa_ b.47.1.4 (A:) Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) {SARS coronavirus [TaxId: 227859]}

SCOPe Domain Coordinates for d4twxa_:

Click to download the PDB-style file with coordinates for d4twxa_.
(The format of our PDB-style files is described here.)

Timeline for d4twxa_:

  • d4twxa_ is new in SCOPe 2.06-stable