Lineage for d4qz4w_ (4qz4 W:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2988339Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 2988340Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 2988529Family d.153.1.4: Proteasome subunits [56251] (4 proteins)
  6. 2988641Protein Proteasome alpha subunit (non-catalytic) [56255] (10 species)
    contains an extension to the common fold at the N-terminus
  7. 2988657Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56257] (240 PDB entries)
    The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
  8. 2989500Domain d4qz4w_: 4qz4 W: [309169]
    Other proteins in same PDB: d4qz4b_, d4qz4c1, d4qz4c2, d4qz4f_, d4qz4g_, d4qz4h_, d4qz4m_, d4qz4p_, d4qz4q1, d4qz4q2, d4qz4t_, d4qz4u_, d4qz4v_
    automated match to d4eu2j_
    complexed with 04c, cl, mes, mg; mutant

Details for d4qz4w_

PDB Entry: 4qz4 (more details), 3 Å

PDB Description: yCP beta5-A49S mutant in complex with the epoxyketone inhibitor ONX 0914
PDB Compounds: (W:) Proteasome subunit beta type-3

SCOPe Domain Sequences for d4qz4w_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4qz4w_ d.153.1.4 (W:) Proteasome alpha subunit (non-catalytic) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
sdpssinggivvamtgkdcvaiacdlrlgsqslgvsnkfekifhyghvflgitglatdvt
tlnemfryktnlyklkeeraiepetftqlvssslyerrfgpyfvgpvvaginsksgkpfi
agfdligcideakdfivsgtasdqlfgmceslyepnlepedlfetisqallnaadrdals
gwgavvyiikkdevvkrylkmrqd

SCOPe Domain Coordinates for d4qz4w_:

Click to download the PDB-style file with coordinates for d4qz4w_.
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Timeline for d4qz4w_: