Lineage for d4qwkz_ (4qwk Z:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2988339Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 2988340Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 2988529Family d.153.1.4: Proteasome subunits [56251] (4 proteins)
  6. 2990986Protein Proteasome beta subunit (catalytic) [56252] (7 species)
  7. 2990995Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56254] (202 PDB entries)
    The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
  8. 2991589Domain d4qwkz_: 4qwk Z: [308904]
    Other proteins in same PDB: d4qwkb_, d4qwkc1, d4qwkc2, d4qwkd_, d4qwke_, d4qwkf_, d4qwkg_, d4qwkh_, d4qwkk_, d4qwkm_, d4qwkp_, d4qwkq1, d4qwkq2, d4qwkr_, d4qwks_, d4qwkt_, d4qwku_, d4qwkv_, d4qwky_
    automated match to d1rypm_
    complexed with 3bv, cl, mes, mg; mutant

Details for d4qwkz_

PDB Entry: 4qwk (more details), 2.8 Å

PDB Description: yCP beta5-A49T-A50V-double mutant in complex with carfilzomib
PDB Compounds: (Z:) Proteasome subunit beta type-6

SCOPe Domain Sequences for d4qwkz_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4qwkz_ d.153.1.4 (Z:) Proteasome beta subunit (catalytic) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
qfnpygdnggtilgiagedfavlagdtrnitdysinsryepkvfdcgdnivmsangfaad
gdalvkrfknsvkwyhfdhndkklsinsaarniqhllygkrffpyyvhtiiagldedgkg
avysfdpvgsyereqcraggaaaslimpfldnqvnfknqyepgtngkvkkplkylsveev
iklvrdsftsaterhiqvgdgleilivtkdgvrkefyelkrd

SCOPe Domain Coordinates for d4qwkz_:

Click to download the PDB-style file with coordinates for d4qwkz_.
(The format of our PDB-style files is described here.)

Timeline for d4qwkz_: