Lineage for d4q1xa_ (4q1x A:)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2391025Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2391026Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2391027Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 protein domains)
    dimer of identical mono-domain chains, each containing (6,10) barrel
  6. 2391043Protein Human immunodeficiency virus type 1 protease [50632] (9 species)
  7. 2391089Species Human immunodeficiency virus 1 [TaxId:11676] [224867] (53 PDB entries)
  8. 2391145Domain d4q1xa_: 4q1x A: [308066]
    automated match to d3ekya_
    complexed with 017, gol, po4; mutant

Details for d4q1xa_

PDB Entry: 4q1x (more details), 1.9 Å

PDB Description: Mutations Outside the Active Site of HIV-1 Protease Alter Enzyme Structure and Dynamic Ensemble of the Active Site to Confer Drug Resistance
PDB Compounds: (A:) Aspartyl protease

SCOPe Domain Sequences for d4q1xa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4q1xa_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus 1 [TaxId: 11676]}

SCOPe Domain Coordinates for d4q1xa_:

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Timeline for d4q1xa_: