Lineage for d4q1bb_ (4q1b B:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2109203Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2109204Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2109205Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 protein domains)
    parallel beta-sheet of 5 strands, order 23145
  6. 2109296Protein Deoxycytidine kinase [89657] (1 species)
  7. 2109297Species Human (Homo sapiens) [TaxId:9606] [89658] (45 PDB entries)
  8. 2109358Domain d4q1bb_: 4q1b B: [308061]
    automated match to d4jlnb_
    complexed with 2y0, udp; mutant

Details for d4q1bb_

PDB Entry: 4q1b (more details), 2.15 Å

PDB Description: Human dCK C4S-S74E mutant in complex with UDP and the inhibitor 7 {N-(2-(3-(4-(((4,6-diaminopyrimidin-2-yl)thio)methyl)-5-propylthiazol-2-yl)phenoxy)ethyl)methanesulfonamide}
PDB Compounds: (B:) Deoxycytidine kinase

SCOPe Domain Sequences for d4q1bb_:

Sequence, based on SEQRES records: (download)

>d4q1bb_ c.37.1.1 (B:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d4q1bb_ c.37.1.1 (B:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4q1bb_:

Click to download the PDB-style file with coordinates for d4q1bb_.
(The format of our PDB-style files is described here.)

Timeline for d4q1bb_:

  • d4q1bb_ is new in SCOPe 2.06-stable