SCOPe 2.08: Domain d4olaa1: 4ola A:23-412

Lineage for d4olaa1 (4ola A:23-412)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.34: SH3-like barrel [50036] (21 superfamilies)
   barrel, partly opened; n*=4, S*=8; meander
   the last strand is interrupted by a turn of 3-10 helix

4. Superfamily b.34.14: PAZ domain [101690] (2 families)

5. Family b.34.14.1: PAZ domain [101691] (6 proteins)

6. Protein Argonaute 2 [101692] (2 species)
   Pfam PF16486; Pfam PF08699; Pfam PF16488

7. Species Human (Homo sapiens) [TaxId:9606] [310963] (4 PDB entries)

8. Domain d4olaa1: 4ola A:23-412 [307903]
   Other proteins in same PDB: d4olaa2, d4olaa3
   protein/RNA complex; complexed with ipa, iph
   has additional subdomain(s) that are not in the common domain

Details for d4olaa1

PDB Entry: 4ola, 2.3 Å

PDB Description: Crystal Structure of Human Argonaute2

PDB Compounds: (A:) Protein argonaute-2

SCOPe Domain Sequences for d4olaa1:

Sequence, based on SEQRES records:

>d4olaa1 b.34.14.1 (A:23-412) Argonaute 2 {Human (Homo sapiens) [TaxId: 9606]}
fkppprpdfgtsgrtiklqanffemdipkidiyhyeldikpekcprrvnreivehmvqhf
ktqifgdrkpvfdgrknlytamplpigrdkvelevtlpgegkdrifkvsikwvscvslqa
lhdalsgrlpsvpfetiqaldvvmrhlpsmrytpvgrsfftasegcsnplgggrevwfgf
hqsvrpslwkmmlnidvsatafykaqpviefvcevldfksieeqqkpltdsqrvkftkei
kglkveithcgqmkrkyrvcnvtrrpashqtfplqqesgqtvectvaqyfkdrhklvlry
phlpclqvgqeqkhtylplevcnivagqrcikkltdnqtstmiratarsapdrqeeiskl
mrsadfntdpyvrefgimvkdemtdvtgrv

Sequence, based on observed residues (ATOM records):

>d4olaa1 b.34.14.1 (A:23-412) Argonaute 2 {Human (Homo sapiens) [TaxId: 9606]}
fkppprpdfgtsgrtiklqanffemdipkidiyhyeldikpekcprrvnreivehmvqhf
ktqifgdrkpvfdgrknlytamplpigrdkvelevtlrifkvsikwvscvslqalhdals
grlvpfetiqaldvvmrhlpsmrytpvgrsfftassnplgggrevwfgfhqsvrpslwkm
mlnidvsatafykaqpviefvcevldfksieqkpltdsqrvkftkeikglkveitrkyrv
cnvtrrpashqtfplqqesgqtvectvaqyfkdrhklvlryphlpclqvgqehtylplev
cnivagqrcikkltdnqtstmiratarsapdrqeeisklmrsadfntdpyvrefgimvkd
emtdvtgrv

Timeline for d4olaa1:

• d4olaa1 first appeared in SCOPe 2.06
  
• d4olaa1 appears in SCOPe 2.07