Lineage for d4na6b_ (4na6 B:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2120592Fold c.50: Macro domain-like [52948] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 6 strands, order 165243, strand 3 is antiparallel to the rest
  4. 2120593Superfamily c.50.1: Macro domain-like [52949] (4 families) (S)
  5. 2120716Family c.50.1.3: Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain-like [310642] (2 protein domains)
    Pfam PF05028
    Contains N- and C-terminal extensions to macrodomain, including Tyr clasp, discussed in PubMed 22609859
  6. 2120717Protein Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain [310785] (3 species)
  7. 2120718Species Mouse (Mus musculus) [TaxId:10090] [311376] (7 PDB entries)
  8. 2120728Domain d4na6b_: 4na6 B: [307765]
    automated match to d3ueka_
    complexed with so4; mutant

Details for d4na6b_

PDB Entry: 4na6 (more details), 2.48 Å

PDB Description: Crystal structure of mouse poly(ADP-ribose) glycohydrolase (PARG) catalytic domain mutant E749N
PDB Compounds: (B:) Poly(ADP-ribose) glycohydrolase

SCOPe Domain Sequences for d4na6b_:

Sequence, based on SEQRES records: (download)

>d4na6b_ c.50.1.3 (B:) Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain {Mouse (Mus musculus) [TaxId: 10090]}
ekkwlgtpieemrkmprcgihlpslrpsashtvtvrvdllragevpkpfpthykdlwdnk
hvkmpcseqnlypvedengertagsrweliqtallnkftrpqnlkdailkynvayskkwd
ftalvdfwdkvleeaeaqhlyqsilpdmvkialclpnictqpipllkqkmnhsvtmsqeq
iasllanaffctfprrnakmkseyssypdinfnrlfegrssrkpeklktlfcyfrrvtek
kptglvtftrqsledfpewercekpltrlhvtyegtiegngrgmlqvdfanrfvgggvtg
aglvqenirflinpelivsrlftevldhnecliitgteqyseytgyaetyrwarshedgs
ekddwqrrcteivaidalhfrryldqfvpekvrrelnkaycgflrpgvpsenlsavatgn
wgcgafggdarlkaliqilaaaaaerdvvyftfgdselmrdiysmhtflterkldvgkvy
klllryyneecrncstpgpdiklypfiyhavessa

Sequence, based on observed residues (ATOM records): (download)

>d4na6b_ c.50.1.3 (B:) Poly(ADP-ribose) glycohydrolase (PARG) catalytic domain {Mouse (Mus musculus) [TaxId: 10090]}
ekkwlgtpieemrkmprcgihlpslrpsashtvtvrvdllragevpkpfpthykdlwdnk
hvkmpcseqnlygsrweliqtallnkftrpqnlkdailkynvayskkwdftalvdfwdkv
leeaeaqhlyqsilpdmvkialclpnictqpipllkqkmnhsvtmsqeqiasllanaffc
tfprrnakmkseyssypdinfnrlfegrssrkpeklktlfcyfrrvtekkptglvtftrq
sledfpewercekpltrlhvtyegtiegngrgmlqvdfanrfvgggvtgaglvqenirfl
inpelivsrlftevldhnecliitgteqyseytgyaetyrwarshedgsekddwqrrcte
ivaidalhfrryldqfvpekvrrelnkaycgflrpgvpsenlsavatgnwgcgafggdar
lkaliqilaaaaaerdvvyftfgdselmrdiysmhtflterkldvgkvyklllryyneec
rncstpgpdiklypfiyhavessa

SCOPe Domain Coordinates for d4na6b_:

Click to download the PDB-style file with coordinates for d4na6b_.
(The format of our PDB-style files is described here.)

Timeline for d4na6b_:

  • d4na6b_ is new in SCOPe 2.06-stable