Lineage for d3zz2a_ (3zz2 A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2220941Protein automated matches [190091] (17 species)
    not a true protein
  7. 2221040Species Human (Homo sapiens) [TaxId:9606] [188447] (653 PDB entries)
  8. 2221399Domain d3zz2a_: 3zz2 A: [306994]
    automated match to d4equa_
    complexed with d88, edo

Details for d3zz2a_

PDB Entry: 3zz2 (more details), 2.2 Å

PDB Description: crystal structure of human serine threonine kinase-10 bound to 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6- methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile apparently modified through radiation damage
PDB Compounds: (A:) serine/threonine-protein kinase 10

SCOPe Domain Sequences for d3zz2a_:

Sequence, based on SEQRES records: (download)

>d3zz2a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ehvrrdldpnevweivgelgdgafgkvykaknketgalaaakvietkseeeledyiveie
ilatcdhpyivkllgayyhdgklwimiefcpggavdaimleldrgltepqiqvvcrqmle
alnflhskriihrdlkagnvlmtlegdirladfgvsaknlktlqkrdsfigtpywmapev
vmcetmkdtpydykadiwslgitliemaqiepphhelnpmrvllkiaksdpptlltpskw
svefrdflkialdknpetrpsaaqllehpfvssitsnkalrelvaeakaevme

Sequence, based on observed residues (ATOM records): (download)

>d3zz2a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ehvrrdldpnevweivgelgdgafgkvykaknketgalaaakvieeeledyiveieilat
cdhpyivkllgayyhdgklwimiefcpggavdaimleldrgltepqiqvvcrqmlealnf
lhskriihrdlkagnvlmtlegdirladfgvsaknlktlqpywmapevvmcetmkdtpyd
ykadiwslgitliemaqiepphhelnpmrvllkiaksdpptlltpskwsvefrdflkial
dknpetrpsaaqllehpfvssitsnkalrelvaeakaevme

SCOPe Domain Coordinates for d3zz2a_:

Click to download the PDB-style file with coordinates for d3zz2a_.
(The format of our PDB-style files is described here.)

Timeline for d3zz2a_: