SCOPe 2.08: Domain d3v4ka_: 3v4k A:

Lineage for d3v4ka_ (3v4k A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.97: Cytidine deaminase-like [53926] (2 superfamilies)
   core: alpha-beta(2)-(alpha-beta)2; 3 layers (a/b/a); mixed beta-sheet of 4 strands, order 2134; strand 1 is antiparallel to the rest

4. Superfamily c.97.1: Cytidine deaminase-like [53927] (7 families)
   contains extra C-terminal strand 5, order 21345

5. Family c.97.1.6: apolipoprotein B messenger RNA-editing enzyme catalytic (APOBEC) cytidine deaminase domains [310632] (5 proteins)
   strand 5 is parallel to strand 4
   Pfam PF08210; Pfam PF05240

6. Protein automated matches [310855] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [311219] (20 PDB entries)

8. Domain d3v4ka_: 3v4k A: [306677]
   automated match to d4xxoa_
   complexed with cl, mg, zn

Details for d3v4ka_

PDB Entry: 3v4k, 1.38 Å

PDB Description: first-in-class small molecule inhibitors of the single-strand dna cytosine deaminase apobec3g

PDB Compounds: (A:) DNA dC->dU-editing enzyme APOBEC-3G

SCOPe Domain Sequences for d3v4ka_:

Sequence; same for both SEQRES and ATOM records:

>d3v4ka_ c.97.1.6 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hsmdpptftfnfnnepwvrgrhetylcyevermhndtwvklnqrrgflanqaphkhgfle
grhaelcfldvipfwkldldqdyrvtcftswspcfscaqemakfisknkhvslciktari
yddqgrcqeglrtlaeagakisimtysefkhcwdtfvdhqgapfqpwdgldehsqdlsgr
lrailq

Timeline for d3v4ka_:

• d3v4ka_ first appeared in SCOPe 2.06
  
• d3v4ka_ appears in SCOPe 2.07