SCOPe 2.06: Domain d3u84b2: 3u84 B:231-581

Lineage for d3u84b2 (3u84 B:231-581)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (25 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.8: TPR-like [48452] (9 families)

5. Family a.118.8.1: Tetratricopeptide repeat (TPR) [48453] (20 proteins)
   this is a repeat family; one repeat unit is 1zb1 A:166-231 found in domain

6. Protein Menin C-terminal domain [310725] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [310974] (23 PDB entries)

8. Domain d3u84b2: 3u84 B:231-581 [306641]
   Other proteins in same PDB: d3u84b1
   automated match to d3u85a2

Details for d3u84b2

PDB Entry: 3u84, 2.5 Å

PDB Description: crystal structure of human menin

PDB Compounds: (B:) Menin

SCOPe Domain Sequences for d3u84b2:

Sequence, based on SEQRES records:

>d3u84b2 a.118.8.1 (B:231-581) Menin C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
drkmevafmvcainpsidlhtdslellqlqqkllwllydlghlerypmalgnladleele
ptpgrpdpltlyhkgiasaktyyrdehiypymylagyhcrnrnvrealqawadtatviqd
ynycredeeiykeffevandvipnllkeaaslleageerpgeqsqgtqsqgsalqdpecf
ahllrfydgickweegsptpvlhvgwatflvqslgrfegqvrqkvrivsgtvagtargpe
ggstaqvpaptaspppegpvltfqsekmkgmkellvatkinssaiklqlta

Sequence, based on observed residues (ATOM records):

>d3u84b2 a.118.8.1 (B:231-581) Menin C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
drkmevafmvcainpsidlhtdslellqlqqkllwllydlghlerypmalgnladleele
ptpgrpdpltlyhkgiasaktyyrdehiypymylagyhcrnrnvrealqawadtatviqd
ynycredeeiykeffevandvipnllkeaaslleasalqdpecfahllrfydgickweeg
sptpvlhvgwatflvqslgrfegqvrqkvrivsagtarggpvltfqsekmkgmkellvat
kinssaiklqlta

Timeline for d3u84b2:

• d3u84b2 is new in SCOPe 2.06-stable
  
• d3u84b2 appears in SCOPe 2.07
  
• d3u84b2 appears in the current release, SCOPe 2.08