SCOPe 2.08: Domain d3re2a1: 3re2 A:4-205

Lineage for d3re2a1 (3re2 A:4-205)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.389: Menin N-terminal domain-like [310556] (1 superfamily)
   Some structural similarity to cysteine proteinases (d.3.1.4) noted in PubMed 22327296

4. Superfamily d.389.1: Menin N-terminal domain-like [310582] (1 family)
   Pfam PF05053

5. Family d.389.1.1: Menin N-terminal domain-like [310623] (2 proteins)

6. Protein Menin N-terminal domain [310724] (2 species)

7. Species Nematostella vectensis [TaxId:45351] [310971] (1 PDB entry)

8. Domain d3re2a1: 3re2 A:4-205 [306445]
   Other proteins in same PDB: d3re2a2
   complexed with gol

Details for d3re2a1

PDB Entry: 3re2, 1.95 Å

PDB Description: Crystal structure of menin reveals the binding site for Mixed Lineage Leukemia (MLL) protein

PDB Compounds: (A:) Predicted protein

SCOPe Domain Sequences for d3re2a1:

Sequence, based on SEQRES records:

>d3re2a1 d.389.1.1 (A:4-205) Menin N-terminal domain {Nematostella vectensis [TaxId: 45351]}
ksipfplkdiksvvevfrqelrndqpnlaqlsivlgffesastmkagdttstpsldeetf
dalhckfmallqrdftfnagglpatreivknvadlvwgclaksyfkdrphiqnlysfltg
nrldcfgvafavvamcqalgyndvhlalsedhawvvfgkdkietaevtwhgkgnedkrgk
pviyqdddrcswlylngnavhc

Sequence, based on observed residues (ATOM records):

>d3re2a1 d.389.1.1 (A:4-205) Menin N-terminal domain {Nematostella vectensis [TaxId: 45351]}
ksipfplkdiksvvevfrqelrndqpnlaqlsivlgffesastmtpsldeetfdalhckf
mallqrdftfnagglpatreivknvadlvwgclaksyfkdrphiqnlysfltgnrldcfg
vafavvamcqalgyndvhlalsedhawvvfgkdkietaevtwhgkgnedkrgkpviyqdd
drcswlylngnavhc

Timeline for d3re2a1:

• d3re2a1 first appeared in SCOPe 2.06
  
• d3re2a1 appears in SCOPe 2.07