SCOPe 2.08: Domain d3g60a1: 3g60 A:33-371

Lineage for d3g60a1 (3g60 A:33-371)

1. Root: SCOPe 2.08

2. Class f: Membrane and cell surface proteins and peptides [56835] (69 folds)

3. Fold f.37: ABC transporter transmembrane region [90122] (1 superfamily)
   multihelical; complex architecture with several transmembrane helices

4. Superfamily f.37.1: ABC transporter transmembrane region [90123] (2 families)
   automatically mapped to Pfam PF00664

5. Family f.37.1.1: ABC transporter transmembrane region [90124] (4 proteins)

6. Protein P-glycoprotein (P-gp) multidrug resistance protein, transmembrane region [310789] (1 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [311046] (1 PDB entry)

8. Domain d3g60a1: 3g60 A:33-371 [305398]
   Other proteins in same PDB: d3g60a3, d3g60a4
   complexed with 0jz

Details for d3g60a1

PDB Entry: 3g60, 4.4 Å

PDB Description: Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

PDB Compounds: (A:) Multidrug resistance protein 1a

SCOPe Domain Sequences for d3g60a1:

Sequence; same for both SEQRES and ATOM records:

>d3g60a1 f.37.1.1 (A:33-371) P-glycoprotein (P-gp) multidrug resistance protein, transmembrane region {Mouse (Mus musculus) [TaxId: 10090]}
vsvltmfryagwldrlymlvgtlaaiihgvalplmmlifgdmtdsfasvgnvsknstnms
eadkramfakleeemttyayyytgigagvlivayiqvsfwclaagrqihkirqkffhaim
nqeigwfdvhdvgelntrltddvskinegigdkigmffqamatffggfiigftrgwkltl
vilaispvlglsagiwakilssftdkelhayakagavaeevlaairtviafggqkkeler
ynnnleeakrlgikkaitanismgaaflliyasyalafwygtslviskeysigqvltvff
svligafsvgqaspnieafanargaayevfkiidnkpsi

Timeline for d3g60a1:

• d3g60a1 first appeared in SCOPe 2.06
  
• d3g60a1 appears in SCOPe 2.07