SCOPe 2.08: Domain d3emla1: 3eml A:3-208,A:222-310

Lineage for d3emla1 (3eml A:3-208,A:222-310)

1. Root: SCOPe 2.08

2. Class f: Membrane and cell surface proteins and peptides [56835] (69 folds)

3. Fold f.13: Class A G protein-coupled receptor (GPCR)-like [81322] (1 superfamily)
   core: up-and-down bundle of seven transmembrane helices tilted 20 degrees with respect to the plane of the membrane

4. Superfamily f.13.1: Class A G protein-coupled receptor (GPCR)-like [81321] (5 families)
   Pfam PF13853. Phylogeny described in PubMed 12761335

5. Family f.13.1.4: MECA receptors [310611] (1 protein)

6. Protein Adenosine A2A receptor [310691] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [310908] (2 PDB entries)

8. Domain d3emla1: 3eml A:3-208,A:222-310 [305292]
   Other proteins in same PDB: d3emla2
   complexed with so4, ste, zma

Details for d3emla1

PDB Entry: 3eml, 2.6 Å

PDB Description: the 2.6 a crystal structure of a human a2a adenosine receptor bound to zm241385.

PDB Compounds: (A:) Human Adenosine A2A receptor/T4 lysozyme chimera

SCOPe Domain Sequences for d3emla1:

Sequence, based on SEQRES records:

>d3emla1 f.13.1.4 (A:3-208,A:222-310) Adenosine A2A receptor {Human (Homo sapiens) [TaxId: 9606]}
imgssvyitvelaiavlailgnvlvcwavwlnsnlqnvtnyfvvslaaadiavgvlaipf
aitistgfcaachgclfiacfvlvltqssifsllaiaidryiairiplrynglvtgtrak
giiaicwvlsfaigltpmlgwnncgqpkegknhsqgcgegqvaclfedvvpmnymvyfnf
facvlvplllmlgvylriflaarrqlXrstlqkevhaakslaiivglfalcwlplhiinc
ftffcpdcshaplwlmylaivlshtnsvvnpfiyayrirefrqtfrkiirshvlrq

Sequence, based on observed residues (ATOM records):

>d3emla1 f.13.1.4 (A:3-208,A:222-310) Adenosine A2A receptor {Human (Homo sapiens) [TaxId: 9606]}
imgssvyitvelaiavlailgnvlvcwavwlnsnlqnvtnyfvvslaaadiavgvlaipf
aitistgfcaachgclfiacfvlvltqssifsllaiaidryiairiplrynglvtgtrak
giiaicwvlsfaigltpmlgwnncgqsqgcgegqvaclfedvvpmnymvyfnffacvlvp
lllmlgvylriflaarrqlXrstlqkevhaakslaiivglfalcwlplhiincftffcpd
cshaplwlmylaivlshtnsvvnpfiyayrirefrqtfrkiirshvlrq

Timeline for d3emla1:

• d3emla1 first appeared in SCOPe 2.06
  
• d3emla1 appears in SCOPe 2.07