Lineage for d1bwca1 (1bwc A:18-165,A:291-363)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2432904Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
    core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
  4. 2432905Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (9 families) (S)
  5. 2433438Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (15 proteins)
    duplication: both domains have similar folds and functions
    most members of the family contain common C-terminal alpha+beta domain
  6. 2433526Protein Glutathione reductase [51944] (3 species)
  7. 2433544Species Human (Homo sapiens) [TaxId:9606] [51945] (23 PDB entries)
  8. 2433577Domain d1bwca1: 1bwc A:18-165,A:291-363 [30459]
    Other proteins in same PDB: d1bwca3
    complexed with aj3, cl, fad

Details for d1bwca1

PDB Entry: 1bwc (more details), 2.1 Å

PDB Description: structure of human glutathione reductase complexed with ajoene inhibitor and subversive substrate
PDB Compounds: (A:) protein (glutathione reductase)

SCOPe Domain Sequences for d1bwca1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1bwca1 c.3.1.5 (A:18-165,A:291-363) Glutathione reductase {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1bwca1:

Click to download the PDB-style file with coordinates for d1bwca1.
(The format of our PDB-style files is described here.)

Timeline for d1bwca1: