Lineage for d1grfa2 (1grf A:166-290)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2849308Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
    core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
  4. 2849309Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (9 families) (S)
  5. 2849878Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (25 proteins)
    duplication: both domains have similar folds and functions
    most members of the family contain common C-terminal alpha+beta domain
  6. 2849979Protein Glutathione reductase, middle domain [418943] (3 species)
  7. 2849989Species Human (Homo sapiens) [TaxId:9606] [419397] (23 PDB entries)
  8. 2850004Domain d1grfa2: 1grf A:166-290 [30458]
    Other proteins in same PDB: d1grfa1, d1grfa3
    complexed with acm, fad, po4

Details for d1grfa2

PDB Entry: 1grf (more details), 2 Å

PDB Description: substrate binding and catalysis by glutathione reductase as derived from refined enzyme: substrate crystal structures at 2 angstroms resolution
PDB Compounds: (A:) glutathione reductase

SCOPe Domain Sequences for d1grfa2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1grfa2 c.3.1.5 (A:166-290) Glutathione reductase, middle domain {Human (Homo sapiens) [TaxId: 9606]}
sqipgaslgitsdgffqleelpgrsvivgagyiavemagilsalgsktslmirhdkvlrs
fdsmistncteelenagvevlkfsqvkevkktlsglevsmvtavpgrlpvmtmipdvdcl
lwaig

SCOPe Domain Coordinates for d1grfa2:

Click to download the PDB-style file with coordinates for d1grfa2.
(The format of our PDB-style files is described here.)

Timeline for d1grfa2: