Lineage for d1xana1 (1xan A:18-165,A:291-363)

  1. Root: SCOPe 2.08
  2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
    core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
  4. Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (9 families) (S)
  5. Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (25 proteins)
    duplication: both domains have similar folds and functions
    most members of the family contain common C-terminal alpha+beta domain
  6. Protein Glutathione reductase, N- and C-terminal domain [418942] (3 species)
  7. Species Human (Homo sapiens) [TaxId:9606] [419396] (23 PDB entries)
  8. Domain d1xana1: 1xan A:18-165,A:291-363 [30449]
    Other proteins in same PDB: d1xana2, d1xana3
    complexed with fad, hxp
    has additional insertions and/or extensions that are not grouped together

Details for d1xana1

PDB Entry: 1xan (more details), 2 Å

PDB Description: human glutathione reductase in complex with a xanthene inhibitor
PDB Compounds: (A:) glutathione reductase

SCOPe Domain Sequences for d1xana1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1xana1 c.3.1.5 (A:18-165,A:291-363) Glutathione reductase, N- and C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
vasydylvigggsgglasarraaelgaraavveshklggtcvnvgcvpkkvmwntavhse
fmhdhadygfpscegkfnwrvikekrdayvsrlnaiyqnnltkshieiirghaaftsdpk
ptievsgkkytaphiliatggmpstpheXrvpntkdlslnklgiqtddkghiivdefqnt
nvkgiyavgdvcgkalltpvaiaagrklahrlfeykedskld

SCOPe Domain Coordinates for d1xana1 are not available.

Timeline for d1xana1:

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Domains from same chain:
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d1xana2, d1xana3