SCOP 1.57: Domain d1grb_2: 1grb 166-290

Lineage for d1grb_2 (1grb 166-290)

1. Root: SCOP 1.57

2. Class c: Alpha and beta proteins (a/b) [51349] (107 folds)

3. Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)

4. Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (5 families)

5. Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (10 proteins)

6. Protein Glutathione reductase [51944] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [51945] (16 PDB entries)

8. Domain d1grb_2: 1grb 166-290 [30448]
   Other proteins in same PDB: d1grb_3

Details for d1grb_2

PDB Entry: 1grb, 1.85 Å

PDB Description: substrate binding and catalysis by glutathione reductase as derived from refined enzyme: substrate crystal structures at 2 angstroms resolution

SCOP Domain Sequences for d1grb_2:

Sequence; same for both SEQRES and ATOM records:

>d1grb_2 c.3.1.5 (166-290) Glutathione reductase {Human (Homo sapiens)}
sqipgaslgitsdgffqleelpgrsvivgagyiavemagilsalgsktslmirhdkvlrs
fdsmistncteelenagvevlkfsqvkevkktlsglevsmvtavpgrlpvmtmipdvdcl
lwaig

Timeline for d1grb_2:

• d1grb_2 first appeared (with stable ids) in SCOP 1.55
  
• d1grb_2 appears in SCOP 1.59
  
• d1grb_2 appears in the current release, SCOPe 2.08, called d1grba2