SCOP 1.69: Domain d1dnc_2: 1dnc 166-290

Lineage for d1dnc_2 (1dnc 166-290)

1. Root: SCOP 1.69

2. Class c: Alpha and beta proteins (a/b) [51349] (136 folds)

3. Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
   core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander

4. Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (5 families)

5. Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (13 proteins)
   duplication: both domains have similar folds and functions
   most members of the family contain common C-terminal alpha+beta domain

6. Protein Glutathione reductase [51944] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [51945] (17 PDB entries)

8. Domain d1dnc_2: 1dnc 166-290 [30444]
   Other proteins in same PDB: d1dnc_3

Details for d1dnc_2

PDB Entry: 1dnc, 1.7 Å

PDB Description: human glutathione reductase modified by diglutathione-dinitroso-iron

SCOP Domain Sequences for d1dnc_2:

Sequence; same for both SEQRES and ATOM records:

>d1dnc_2 c.3.1.5 (166-290) Glutathione reductase {Human (Homo sapiens)}
sqipgaslgitsdgffqleelpgrsvivgagyiavemagilsalgsktslmirhdkvlrs
fdsmistncteelenagvevlkfsqvkevkktlsglevsmvtavpgrlpvmtmipdvdcl
lwaig

Timeline for d1dnc_2:

• d1dnc_2 first appeared (with stable ids) in SCOP 1.55
  
• d1dnc_2 appears in SCOP 1.67
  
• d1dnc_2 appears in SCOP 1.71
  
• d1dnc_2 appears in the current release, SCOPe 2.08, called d1dnca2