SCOPe 2.08: Domain d2pz3a2: 2pz3 A:61-181

Lineage for d2pz3a2 (2pz3 A:61-181)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.66: Transducin (alpha subunit), insertion domain [47894] (1 superfamily)
   5 helices; folded leaf

4. Superfamily a.66.1: Transducin (alpha subunit), insertion domain [47895] (1 family)
   this domain interrupts the G-protein common fold

5. Family a.66.1.1: Transducin (alpha subunit), insertion domain [47896] (1 protein)

6. Protein Transducin (alpha subunit), insertion domain [47897] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [158559] (9 PDB entries)

8. Domain d2pz3a2: 2pz3 A:61-181 [304387]
   Other proteins in same PDB: d2pz3a1
   automated match to d3umsa1
   complexed with alf, gdp, mg; mutant

Details for d2pz3a2

PDB Entry: 2pz3, 2.42 Å

PDB Description: Crystal structure of the AMF-bound conformation of a G-alpha-i1 mutant with enhanced GTPase activity

PDB Compounds: (A:) Guanine nucleotide-binding protein G(i), alpha-1 subunit

SCOPe Domain Sequences for d2pz3a2:

Sequence, based on SEQRES records:

>d2pz3a2 a.66.1.1 (A:61-181) Transducin (alpha subunit), insertion domain {Human (Homo sapiens) [TaxId: 9606]}
yseeeckqykavvysntiqsiiaiiramgrlkidfgdsaraddarqlfvlagaaeegfmt
aelagvikrlwkdsgvqacfnrsreyqlndsaayylndldriaqpnyiptqqdvlrtrvk
t

Sequence, based on observed residues (ATOM records):

>d2pz3a2 a.66.1.1 (A:61-181) Transducin (alpha subunit), insertion domain {Human (Homo sapiens) [TaxId: 9606]}
yseeeckqykavvysntiqsiiaiiramgrlkidfgdsaraddarqlfvlagaaefmtae
lagvikrlwkdsgvqacfnrsreyqlndsaayylndldriaqpnyipqqdvlrtrvkt

Timeline for d2pz3a2:

• d2pz3a2 first appeared in SCOPe 2.06
  
• d2pz3a2 appears in SCOPe 2.07