SCOPe 2.07: Domain d2g8ob_: 2g8o B:

Lineage for d2g8ob_ (2g8o B:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein Thymidylate synthase [55833] (7 species)

7. Species Escherichia coli [TaxId:562] [55834] (71 PDB entries)

8. Domain d2g8ob_: 2g8o B: [303925]
   automated match to d1f4ba_
   complexed with cb3, ump

Details for d2g8ob_

PDB Entry: 2g8o, 1.3 Å

PDB Description: High resolution structure of Escherichia coli thymidylate synthase ternary complex with dUMP and a cofactor analog, CB3717

PDB Compounds: (B:) Thymidylate synthase

SCOPe Domain Sequences for d2g8ob_:

Sequence; same for both SEQRES and ATOM records:

>d2g8ob_ d.117.1.1 (B:) Thymidylate synthase {Escherichia coli [TaxId: 562]}
mkqylelmqkvldegtqkndrtgtgtlsifghqmrfnlqdgfplvttkrchlrsiihell
wflqgdtniaylhennvtiwdewadengdlgpvygkqwrawptpdgrhidqittvlnqlk
ndpdsrriivsawnvgeldkmalapchaffqfyvadgklscqlyqrscdvflglpfnias
yallvhmmaqqcdlevgdfvwtggdthlysnhmdqthlqlsreprplpkliikrkpesif
dyrfedfeiegydphpgikapvai

Timeline for d2g8ob_:

• d2g8ob_ first appeared in SCOPe 2.06
  
• d2g8ob_ appears in the current release, SCOPe 2.08