Lineage for d2ewda4 (2ewd A:165-333)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2556795Fold d.162: LDH C-terminal domain-like [56326] (1 superfamily)
    unusual fold, defines family
  4. 2556796Superfamily d.162.1: LDH C-terminal domain-like [56327] (3 families) (S)
  5. 2556797Family d.162.1.1: Lactate & malate dehydrogenases, C-terminal domain [56328] (5 proteins)
    N-terminal domain is NAD-binding module (alpha/beta Rossmann-fold domain)
    automatically mapped to Pfam PF02866
  6. 2556804Protein Lactate dehydrogenase [56339] (20 species)
  7. 2556839Species Cryptosporidium parvum [TaxId:5807] [225186] (10 PDB entries)
  8. 2556840Domain d2ewda4: 2ewd A:165-333 [303803]
    Other proteins in same PDB: d2ewda3, d2ewdb3
    automated match to d4nd5a2
    complexed with a3d, gol, pyr

Details for d2ewda4

PDB Entry: 2ewd (more details), 2 Å

PDB Description: Crystal structure of the Lactate Dehydrogenase from Cryptosporidium parvum complexed with substrate (Pyruvic acid) and cofactor analog (3-Acetylpyridine adenine dinucleotide).
PDB Compounds: (A:) lactate dehydrogenase,

SCOPe Domain Sequences for d2ewda4:

Sequence; same for both SEQRES and ATOM records: (download)

>d2ewda4 d.162.1.1 (A:165-333) Lactate dehydrogenase {Cryptosporidium parvum [TaxId: 5807]}
gvldssrfrtfiaqhfgvnasdvsanvigghgdgmvpatssvsvggvplssfikqglitq
eqideivchtriawkevadnlktgtayfapaaaavkmaeaylkdkkavvpcsafcsnhyg
vkgiymgvptiigkngvedileldltpleqkllgesinevntiskvldnap

SCOPe Domain Coordinates for d2ewda4:

Click to download the PDB-style file with coordinates for d2ewda4.
(The format of our PDB-style files is described here.)

Timeline for d2ewda4:

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d2ewda3