Lineage for d1tbma_ (1tbm A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2018901Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 2018902Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families) (S)
  5. 2018992Family a.211.1.2: PDEase [48548] (7 proteins)
    Pfam PF00233; multihelical; can be divided into three subdomains
  6. 2019228Protein High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, PDE9A [109942] (2 species)
  7. 2019232Species Human (Homo sapiens) [TaxId:9606] [109943] (20 PDB entries)
    Uniprot O76083 241-566
  8. 2019243Domain d1tbma_: 1tbm A: [303079]
    automated match to d2hd1a_
    complexed with ibm, mg, zn

Details for d1tbma_

PDB Entry: 1tbm (more details), 2.23 Å

PDB Description: Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor IBMX binding
PDB Compounds: (A:) cGMP phosphodiesterase A2

SCOPe Domain Sequences for d1tbma_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1tbma_ a.211.1.2 (A:) High-affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, PDE9A {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1tbma_:

Click to download the PDB-style file with coordinates for d1tbma_.
(The format of our PDB-style files is described here.)

Timeline for d1tbma_: