Lineage for d1diaa1 (1dia A:127-296)

  1. Root: SCOP 1.57
  2. 64291Class c: Alpha and beta proteins (a/b) [51349] (107 folds)
  3. 66135Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
  4. 66136Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (9 families) (S)
  5. 66936Family c.2.1.7: Amino-acid dehydrogenase-like, C-terminal domain [51883] (5 proteins)
  6. 67005Protein Methylenetetrahydrofolate dehydrogenase/cyclohydrolase [51894] (3 species)
  7. 67011Species Human (Homo sapiens) [TaxId:9606] [51895] (4 PDB entries)
  8. 67014Domain d1diaa1: 1dia A:127-296 [30280]
    Other proteins in same PDB: d1diaa2, d1diab2

Details for d1diaa1

PDB Entry: 1dia (more details), 2.2 Å

PDB Description: human methylenetetrahydrofolate dehydrogenase / cyclohydrolase complexed with nadp and inhibitor ly249543

SCOP Domain Sequences for d1diaa1:

Sequence, based on SEQRES records: (download)

>d1diaa1 c.2.1.7 (A:127-296) Methylenetetrahydrofolate dehydrogenase/cyclohydrolase {Human (Homo sapiens)}
ltsinagrlargdlndcfipctpkgcleliketgvpiagrhavvvgrskivgapmhdlll
wnnatvttchsktahldeevnkgdilvvatgqpemvkgewikpgaividcginyvpddkk
pngrkvvgdvaydeakerasfitpvpggvgpmtvamlmqstvesakrfle

Sequence, based on observed residues (ATOM records): (download)

>d1diaa1 c.2.1.7 (A:127-296) Methylenetetrahydrofolate dehydrogenase/cyclohydrolase {Human (Homo sapiens)}
ltsinagrlargdlndcfipctpkgcleliketgvpiagrhavvvgrskivgapmhdlll
wnnatvttchsktahldeevnkgdilvvatgqpemvkgewikpgaividcginykvvgdv
aydeakerasfitpvpggvgpmtvamlmqstvesakrfle

SCOP Domain Coordinates for d1diaa1:

Click to download the PDB-style file with coordinates for d1diaa1.
(The format of our PDB-style files is described here.)

Timeline for d1diaa1:

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Domains from same chain:
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d1diaa2